Varaico: Literature-Extracted Genetic Variants

Gene:CASP3
Variant:p.E17K
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CASP3

NM_004346.4:p.E17K

Associated Papers

Multi-selective RAS(ON) Inhibition Targets Oncogenic RAS Mutations and Overcomes RAS/MAPK-Mediated Resistance to FLT3 and BCL2 Inhibitors in Acute Myeloid Leukemia.

Popescu B et al.

Biorxiv : the Preprint Server for Biology, 2025

40661530 (PubMed )
Supplement: media-1.pdf

Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML.

Popescu B et al.

Cell Reports. Medicine, 2023

Fine mapping of the N-terminal cytotoxicity region of Clostridium perfringens enterotoxin by site-directed mutagenesis.

Smedley JG et al.

Infection and Immunity, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."