Varaico: Literature-Extracted Genetic Variants

Gene:CASP6
Variant:p.C163S
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CASP6

NM_001226.4:p.C163S

Associated Papers

Chemoproteomics Using Nucleotide Acyl Phosphates Reveals an ATP Binding Site at the Dimer Interface of Procaspase-6.

Okerberg ES et al.

Biochemistry, 2019

Tri-arginine exosite patch of caspase-6 recruits substrates for hydrolysis.

MacPherson DJ et al.

The Journal of Biological Chemistry, 2019

Tumor-Associated Mutations in Caspase-6 Negatively Impact Catalytic Efficiency.

Dagbay KB et al.

Biochemistry, 2017

Zinc-mediated allosteric inhibition of caspase-6.

Velázquez-Delgado EM et al.

The Journal of Biological Chemistry, 2012

IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1.

Aebischer J et al.

Cell Death and Differentiation, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."