Varaico: Literature-Extracted Genetic Variants

Gene:CASP6
Variant:p.R65W
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CASP6

NM_001226.4:p.R65W

Associated Papers

Insights into Caspase-6 Mutations and Neuropathology in Huntington's Disease and Psychiatric Disorders: A Structural Genomics and Drug Repurposing Approach.

Hakami MA et al.

Molecular Neurobiology, 2025

Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration.

Zhou L et al.

Scientific Reports, 2021

Identification of Allosteric Inhibitors against Active Caspase-6.

Tubeleviciute-Aydin A et al.

Scientific Reports, 2019

Rare human Caspase-6-R65W and Caspase-6-G66R variants identify a novel regulatory region of Caspase-6 activity.

Tubeleviciute-Aydin A et al.

Scientific Reports, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."