Varaico: Literature-Extracted Genetic Variants

Gene:CASP8
Variant:p.D73A
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CASP8

NM_001372051.1:p.D73A

Associated Papers

Critical role for caspase-8 in epidermal growth factor signaling.

Finlay D et al.

Cancer Research, 2009

Death effector domain DEDa, a self-cleaved product of caspase-8/Mch5, translocates to the nucleus by binding to ERK1/2 and upregulates procaspase-8 expression via a p53-dependent mechanism.

Yao Z et al.

The Embo Journal, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."