Varaico: Literature-Extracted Genetic Variants

Gene:CASP8
Variant:p.D223A
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CASP8

NM_001372051.1:p.D223A

Associated Papers

Caspase-8-dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality.

Demarco B et al.

Science Advances, 2020

Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.

Ding J et al.

Molecular Cell, 2019

Cancer-associated missense mutations of caspase-8 activate nuclear factor-κB signaling.

Ando M et al.

Cancer Science, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."