Varaico: Literature-Extracted Genetic Variants

Gene:CASP9
Variant:p.C287S
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CASP9

NM_001229.5:p.C287S

Associated Papers

Expression and functional analysis of Apaf-1 isoforms. Extra Wd-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9.

Benedict MA et al.

The Journal of Biological Chemistry, 2000

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis.

Hu Y et al.

The Embo Journal, 1999

WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation.

Hu Y et al.

The Journal of Biological Chemistry, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."