Associated Papers
An activating calcium-sensing receptor variant with biased signaling reveals a critical residue for Gα11 coupling.
Benson MR et al.
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 2025
39658204 (PubMed )
Supplement: revised_supplementary_appendix_clean_zjae199.docx
G protein-coupled receptor (GPCR) gene variants and human genetic disease.
Thompson MD et al.
Critical Reviews in Clinical Laboratory Sciences, 2024
Structural basis for activation and allosteric modulation of full-length calcium-sensing receptor.
Wen T et al.
Science Advances, 2021
Calcium-sensing receptor residues with loss- and gain-of-function mutations are located in regions of conformational change and cause signalling bias.
Gorvin CM et al.
Human Molecular Genetics, 2018
G protein-coupled receptor pharmacogenetics.
Thompson MD et al.
Methods in Molecular Biology (clifton, N.j.), 2008
Impact of GPCRs in clinical medicine: monogenic diseases, genetic variants and drug targets.
Insel PA et al.
Biochimica Et Biophysica Acta, 2007
The G protein-coupled receptors: pharmacogenetics and disease.
Thompson MD et al.
Critical Reviews in Clinical Laboratory Sciences, 2005
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