Varaico: Literature-Extracted Genetic Variants

Gene:CASR
Variant:p.E767A
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CASR

NM_000388.4:p.E767A

Associated Papers

Dual Action Calcium-Sensing Receptor Modulator Unmasks Novel Mode-Switching Mechanism.

Gregory KJ et al.

Acs Pharmacology & Translational Science, 2018

Towards a structural understanding of allosteric drugs at the human calcium-sensing receptor.

Leach K et al.

Cell Research, 2016

A missense mutation in the seven-transmembrane domain of the human Ca2+ receptor converts a negative allosteric modulator into a positive allosteric modulator.

Hu J et al.

The Journal of Biological Chemistry, 2006

The role of cysteines and charged amino acids in extracellular loops of the human Ca(2+) receptor in cell surface expression and receptor activation processes.

Ray K et al.

Endocrinology, 2004

Identification of acidic residues in the extracellular loops of the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+ and a positive allosteric modulator.

Hu J et al.

The Journal of Biological Chemistry, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."