Varaico: Literature-Extracted Genetic Variants

Gene:CASR
Variant:p.T888A
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CASR

NM_000388.4:p.T888A

Associated Papers

Both calcium-sensing receptor intracellular C-terminal domains support homodimer signaling.

Binmahfouz LS et al.

Molecular Pharmacology, 2025

Allosteric modulation and G-protein selectivity of the Ca2+-sensing receptor.

He F et al.

Nature, 2024

Calcium-sensing receptor signaling - How human disease informs biology.

Gorvin CM

Current Opinion in Endocrine and Metabolic Research, 2021

International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function.

Leach K et al.

Pharmacological Reviews, 2020

Identification of Serine-875 as an Inhibitory Phosphorylation Site in the Calcium-Sensing Receptor.

Binmahfouz LS et al.

Molecular Pharmacology, 2019

Calcium-sensing receptor (CaSR): pharmacological properties and signaling pathways.

Conigrave AD et al.

Best Practice & Research. Clinical Endocrinology & Metabolism, 2013

Large putative PEST-like sequence motif at the carboxyl tail of human calcium receptor directs lysosomal degradation and regulates cell surface receptor level.

Zhuang X et al.

The Journal of Biological Chemistry, 2012

A novel mutation of the primary protein kinase C phosphorylation site in the calcium-sensing receptor causes autosomal dominant hypocalcemia.

Lazarus S et al.

European Journal of Endocrinology, 2011

Calcimimetic R-568 effects on activity of R990G polymorphism of calcium-sensing receptor.

Terranegra A et al.

Journal of Molecular Endocrinology, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."