Varaico: Literature-Extracted Genetic Variants

Gene:CAST
Variant:p.P301L
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CAST

NM_001750.7:p.P301L

Associated Papers

Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice.

Liu M et al.

Journal of Alzheimer's Disease : Jad, 2019

Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease.

Nixon RA

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2017

The Role of MAPT in Neurodegenerative Diseases: Genetics, Mechanisms and Therapy.

Zhang CC et al.

Molecular Neurobiology, 2016

Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L mice.

Rao MV et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."