Varaico: Literature-Extracted Genetic Variants

Gene:CAV1
Variant:p.Y14F
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CAV1

NM_001753.5:p.Y14F

Associated Papers

Endothelial cell CD36 regulates membrane ceramide formation, exosome fatty acid transfer and circulating fatty acid levels.

Peche VS et al.

Nature Communications, 2023

Schistosomiasis-associated pulmonary hypertension unveils disrupted murine gut-lung microbiome and reduced endoprotective Caveolin-1/BMPR2 expression.

Marinho Y et al.

Frontiers in Immunology, 2023

Caveolin-1 controls mitochondrial damage and ROS production by regulating fission - fusion dynamics and mitophagy.

Jiang Y et al.

Redox Biology, 2022

Quantitative targeted proteomic analysis of potential markers of tyrosine kinase inhibitor (TKI) sensitivity in EGFR mutated lung adenocarcinoma.

Awasthi S et al.

Journal of Proteomics, 2018

Extracellular matrix-specific Caveolin-1 phosphorylation on tyrosine 14 is linked to augmented melanoma metastasis but not tumorigenesis.

Ortiz R et al.

Oncotarget, 2016

Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells.

Boothe T et al.

Molecular Metabolism, 2016

Overexpression of caveolin-1 is sufficient to phenocopy the behavior of a disease-associated mutant.

Hanson CA et al.

Traffic (copenhagen, Denmark), 2013

Ubiquitination of the N-terminal region of caveolin-1 regulates endosomal sorting by the VCP/p97 AAA-ATPase.

Kirchner P et al.

The Journal of Biological Chemistry, 2013

Tyrosine-phosphorylated caveolin-1 (Tyr-14) increases sensitivity to paclitaxel by inhibiting BCL2 and BCLxL proteins via c-Jun N-terminal kinase (JNK).

Shajahan AN et al.

The Journal of Biological Chemistry, 2012

Caveolin-1 opens endothelial cell junctions by targeting catenins.

Kronstein R et al.

Cardiovascular Research, 2012

Clathrin-independent internalization of normal cellular prion protein in neuroblastoma cells is associated with the Arf6 pathway.

Kang YS et al.

Journal of Cell Science, 2009

Caveolin-1-dependent and -independent membrane domains.

Le Lay S et al.

Journal of Lipid Research, 2009

Concerted regulation of focal adhesion dynamics by galectin-3 and tyrosine-phosphorylated caveolin-1.

Goetz JG et al.

The Journal of Cell Biology, 2008

c-Abl is required for staurosporine-induced caspase activity.

Oxhorn BC et al.

Proceedings of the Western Pharmacology Society, 2005

A phosphotyrosine-dependent protein interaction screen reveals a role for phosphorylation of caveolin-1 on tyrosine 14: recruitment of C-terminal Src kinase.

Cao H et al.

The Journal of Biological Chemistry, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."