Associated Papers
Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases.
Chatrin C et al.
Science Advances, 2020
A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants.
Gabrielsen M et al.
Molecular Cell, 2017
Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation.
Buetow L et al.
Bmc Biology, 2016
Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl.
Dou H et al.
Nature Structural & Molecular Biology, 2012
Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations.
Kassenbrock CK et al.
The Journal of Biological Chemistry, 2004
RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation.
Thien CB et al.
Molecular Cell, 2001
Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene.
Andoniou CE et al.
The Embo Journal, 1994
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