Associated Papers
CBL-Mutated Juvenile Myelomonocytic Leukaemia With Loss of Heterozygosity on 11q Detected by Microarray: Not Always Such a Favourable Outcome.
Salvadores-Álvarez V et al.
International Journal of Laboratory Hematology, 2025
Expanded noninvasive prenatal screening for dominant single-gene disorders: proof-of-concept, performance, and challenges.
Chen S et al.
American Journal of Obstetrics and Gynecology, 2025
Locking CBL TKBD in its native conformation presents a novel therapeutic opportunity in mutant CBL-dependent leukemia.
Ahmed SF et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy, 2025
Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation.
Bohlen J et al.
The Journal of Clinical Investigation, 2024
Genomic ascertainment to quantify prevalence and cancer risk in adults with pathogenic and likely pathogenic germline variants in RASopathy genes.
Kim J et al.
Medrxiv : the Preprint Server for Health Sciences, 2024
Genetic Study of HGF-MET Signaling Pathway in Primary Lymphedema Patients: Supporting Evidence for Loss of Function Variants in HGF.
Kozacikova R et al.
Lymphology, 2024
Interaction between myelodysplasia-related gene mutations and ontogeny in acute myeloid leukemia.
McCarter JGW et al.
Blood Advances, 2023
The longitudinal dynamics and natural history of clonal haematopoiesis.
Fabre MA et al.
Nature, 2022
Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway.
Zhang X et al.
Cancer Cell International, 2022
HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia.
Zhu G et al.
Nature Communications, 2021
E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK-CBL-CIN85 axis.
Ahmed SF et al.
Oncogene, 2021
Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.
Hescheler DA et al.
Frontiers in Endocrinology, 2021
Estimating dispensable content in the human interactome.
Ghadie M et al.
Nature Communications, 2019
Distinct age-associated molecular profiles in acute myeloid leukemia defined by comprehensive clinical genomic profiling.
Tarlock K et al.
Oncotarget, 2018
Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation.
Buetow L et al.
Bmc Biology, 2016
UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO.
Goyama S et al.
Leukemia, 2016
The genomic landscape of juvenile myelomonocytic leukemia.
Stieglitz E et al.
Nature Genetics, 2015
[Diagnostic molecular pathology of lymphatic and myeloid neoplasms].
Klapper W et al.
Der Pathologe, 2015
Applicability of next-generation sequencing to decalcified formalin-fixed and paraffin-embedded chronic myelomonocytic leukaemia samples.
Bernard V et al.
International Journal of Clinical and Experimental Pathology, 2014
CBL enhances breast tumor formation by inhibiting tumor suppressive activity of TGF-β signaling.
Kang JM et al.
Oncogene, 2012
Clinical and genetic study of 46 Italian patients with primary lymphedema.
Michelini S et al.
Lymphology, 2012
A high occurrence of acquisition and/or expansion of C-CBL mutant clones in the progression of high-risk myelodysplastic syndrome to acute myeloid leukemia.
Kao HW et al.
Neoplasia (new York, N.y.), 2011
[Gain-of-function mutation of c-CBL tumor suppressor gene in myeloid neoplasms].
Ogawa S
[rinsho Ketsueki] the Japanese Journal of Clinical Hematology, 2011
Recent advances in the pathogenesis and treatment of juvenile myelomonocytic leukaemia.
Loh ML
British Journal of Haematology, 2011
Genetic typing of CBL, ASXL1, RUNX1, TET2 and JAK2 in juvenile myelomonocytic leukaemia reveals a genetic profile distinct from chronic myelomonocytic leukaemia.
Pérez B et al.
British Journal of Haematology, 2010
Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia.
Niemeyer CM et al.
Nature Genetics, 2010
Cbl and human myeloid neoplasms: the Cbl oncogene comes of age.
Kales SC et al.
Cancer Research, 2010
Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms.
Ogawa S et al.
Cell Cycle (georgetown, Tex.), 2010
Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.
Sanada M et al.
Nature, 2009