Varaico: Literature-Extracted Genetic Variants

Gene:CCL11
Variant:p.A23T
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CCL11

NM_002986.3:p.A23T

Associated Papers

Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction network.

Kleist AB et al.

Cell, 2025

40273912 (PubMed )
Supplement: NIHMS2076408-supplement-MMC4.xlsx › Supplementary_Table_4

Association of +67 G/A and -426 T/C Polymorphism in Eotaxin (CCL11) Gene with Psoriasis Phenotypes.

Vašků V et al.

Genes, 2025

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

39991480 (PubMed )
Supplement: mmc5.xlsx › Sheet1

Bioinformatics Study on Site-Specific Variations of Eotaxin-3, a Key Chemokine in Eosinophilic Esophagitis (EoE).

Giordano D et al.

Genes, 2024

39202432 (PubMed )
Supplement: genes-15-01073-s001.zip › Supplementary_Table_S1.pdf

Association between CCL5, CCL11, and CCL17 polymorphisms and atopic dermatitis risk: A systematic review and meta-analysis.

Zou C et al.

Medicine, 2024

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.

Yu H et al.

Elife, 2024

38277211 (PubMed )
Supplement: elife-89762-supp1.xlsx › Variants

Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.

Yu H et al.

Biorxiv : the Preprint Server for Biology, 2023

37292598 (PubMed )
Supplement: media-1.xlsx › Variants

Sex and APOE ε4 carrier effects on atrophy, amyloid PET, and tau PET burden in early-onset Alzheimer's disease.

Nemes S et al.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2023

Comprehensive analysis of chemokine gene polymorphisms in Korean children with autoimmune thyroid disease.

Shin C et al.

Scientific Reports, 2023

Coronary Heart Disease in Type 2 Diabetes Mellitus: Genetic Factors and Their Mechanisms, Gene-Gene, and Gene-Environment Interactions in the Asian Populations.

Zarkasi KA et al.

International Journal of Environmental Research and Public Health, 2022

Why does SARS-CoV-2 hit in different ways? Host genetic factors can influence the acquisition or the course of COVID-19.

Monticelli M et al.

European Journal of Medical Genetics, 2021

33872774 (PubMed )
Supplement: mmc2.xlsx › Foglio1

Identification of somatic alterations in lipoma using whole exome sequencing.

Kanojia D et al.

Scientific Reports, 2019

31591430 (PubMed )
Supplement: 41598_2019_50805_MOESM2_ESM.xlsx › SuppTable_10

Inflammatory chemokine eotaxin-1 is correlated with age in heroin dependent patients under methadone maintenance therapy.

Kuo HW et al.

Drug and Alcohol Dependence, 2018

SNPs in inflammatory genes CCL11, CCL4 and MEFV in a fibromyalgia family study.

Zhang Z et al.

Plos One, 2018

Whole-genome sequencing suggests a chemokine gene cluster that modifies age at onset in familial Alzheimer's disease.

Lalli MA et al.

Molecular Psychiatry, 2015

The age factor in Alzheimer's disease.

Guerreiro R et al.

Genome Medicine, 2015

Inherited variants in regulatory T cell genes and outcome of ovarian cancer.

Goode EL et al.

Plos One, 2013

23382860 (PubMed )
Supplement: pone.0053903.s002.xlsx › Supplemental_Table_2

Epigenome-wide analysis in familial hypercholesterolemia identified new loci associated with high-density lipoprotein cholesterol concentration.

Guay SP et al.

Epigenomics, 2012

Association between three single nucleotide polymorphisms in eotaxin (CCL 11) gene, hexanucleotide repetition upstream, severity and course of coronary atherosclerosis.

Máchal J et al.

Journal of Applied Genetics, 2012

Exome sequencing of only seven Qataris identifies potentially deleterious variants in the Qatari population.

Rodriguez-Flores JL et al.

Plos One, 2012

23139751 (PubMed )
Supplement: pone.0047614.s009.pdf

Lack of association between eotaxin-1 gene polymorphisms and nasal polyposis.

Ekinci S et al.

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-head and Neck Surgery, 2011

Genetic variation, β-blockers, and perioperative myocardial infarction.

Nagele P et al.

Anesthesiology, 2011

β-Adrenergic receptor gene polymorphism is a genetic risk factor for cardiovascular disease: a cohort study with hypertensive patients.

Iwamoto Y et al.

Hypertension Research : Official Journal of the Japanese Society of Hypertension, 2011

Independent predictive roles of eotaxin Ala23Thr, paraoxonase 2 Ser311Cys and beta-adrenergic receptor Trp64Arg polymorphisms on cardiac disease in Type 2 Diabetes--an 8-year prospective cohort analysis of 1297 patients.

Wang Y et al.

Diabetic Medicine : a Journal of the British Diabetic Association, 2010

Investigation of the eotaxin gene -426C-->T, -384A-->G and 67G-->a single-nucleotide polymorphisms and atopic dermatitis in Italian children using family-based association methods.

Rigoli L et al.

Clinical and Experimental Dermatology, 2008

Genetic susceptibility to atopic dermatitis.

Kiyohara C et al.

Allergology International : Official Journal of the Japanese Society of Allergology, 2008

Pharmacogenomics in acute coronary syndrome.

Remmler C et al.

Expert Opinion on Pharmacotherapy, 2008

Identification of novel single nucleotide polymorphisms in inflammatory genes as risk factors associated with trachomatous trichiasis.

Atik B et al.

Plos One, 2008

The polymorphisms of Eotaxin 1 and CCR3 genes influence on serum IgE, Eotaxin levels and mild asthmatic children in Taiwan.

Wang TN et al.

Allergy, 2007

A hexanucleotide repeat upstream of eotaxin gene promoter is associated with asthma, serum total IgE and plasma eotaxin levels.

Batra J et al.

Journal of Medical Genetics, 2007

Complex gene-gene interactions in multiple sclerosis: a multifactorial approach reveals associations with inflammatory genes.

Motsinger AA et al.

Neurogenetics, 2007

Influence of eotaxin 67G>A polymorphism on plasma eotaxin concentrations in myocardial infarction survivors and healthy controls.

Sheikine Y et al.

Atherosclerosis, 2006

Genetic factors for obesity.

Yamada Y et al.

International Journal of Molecular Medicine, 2006

Genetic risk for atherothrombotic cerebral infarction in individuals stratified by sex or conventional risk factors for atherosclerosis.

Yamaguchi S et al.

International Journal of Molecular Medicine, 2006

Assessment of genetic factors for type 2 diabetes mellitus.

Yamada Y et al.

International Journal of Molecular Medicine, 2006

An investigation of polymorphisms in the 17q11.2-12 CC chemokine gene cluster for association with multiple sclerosis in Australians.

Bugeja MJ et al.

Bmc Medical Genetics, 2006

Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans.

Brassat D et al.

Genes and Immunity, 2006

Polymorphism in the beta2-adrenergic receptor and lipoprotein lipase genes as risk determinants for idiopathic venous thromboembolism: a multilocus, population-based, prospective genetic analysis.

Zee RY et al.

Circulation, 2006

Multi-locus candidate gene polymorphisms and risk of myocardial infarction: a population-based, prospective genetic analysis.

Zee RY et al.

Journal of Thrombosis and Haemostasis : Jth, 2006

Eotaxin polymorphisms and serum total IgE levels in children with asthma.

Raby BA et al.

The Journal of Allergy and Clinical Immunology, 2006

Interaction between inflammation-related gene polymorphisms and cigarette smoking on the risk of myocardial infarction in the Physician's Health Study.

Rosner SA et al.

Human Genetics, 2005

A single nucleotide polymorphism on the promoter of eotaxin1 associates with its mRNA expression and asthma phenotypes.

Chang HS et al.

Journal of Immunology (baltimore, Md. : 1950), 2005

The suggestive association of eotaxin-2 and eotaxin-3 gene polymorphisms in Korean population with allergic rhinitis.

Chae SC et al.

Immunogenetics, 2005

Analysis of the polymorphisms in eotaxin gene family and their association with asthma, IgE, and eosinophil.

Chae SC et al.

Biochemical and Biophysical Research Communications, 2004

Threonine for alanine substitution in the eotaxin (CCL11) gene and the risk of incident myocardial infarction.

Zee RY et al.

Atherosclerosis, 2004

Linkage and association with the NOS2A locus on chromosome 17q11 in multiple sclerosis.

Barcellos LF et al.

Annals of Neurology, 2004

Gene interactions and stroke risk in children with sickle cell anemia.

Hoppe C et al.

Blood, 2004

Polymorphism in the P-selectin and interleukin-4 genes as determinants of stroke: a population-based, prospective genetic analysis.

Zee RY et al.

Human Molecular Genetics, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."