Varaico: Literature-Extracted Genetic Variants

Gene:CCND1
Variant:p.Y44D
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CCND1

NM_053056.3:p.Y44D

Associated Papers

Functional genomics and tumor microenvironment analysis reveal prognostic biological subtypes in Mantle cell lymphoma.

Sharma S et al.

Nature Communications, 2025

Clonal hematopoiesis is associated with distinct rheumatoid arthritis phenotypes.

Hiitola E et al.

Science Advances, 2025

40305610 (PubMed )
Supplement: sciadv.adt9846_tables_s1_to_s13.zip › adt9846_tables_s1_to_s13.xlsx › S4

Large B-cell lymphomas with CCND1 rearrangement have different immunoglobulin gene breakpoints and genomic profile than mantle cell lymphoma.

Özoğul E et al.

Blood Cancer Journal, 2024

39313500 (PubMed )
Supplement: 41408_2024_1146_MOESM2_ESM.xlsx › S10

Biological and clinical determinants shaping heterogeneity in mantle cell lymphoma.

López C et al.

Blood Advances, 2024

Mutational landscape of cancer-driver genes across human cancers.

Sinkala M

Scientific Reports, 2023

37550388 (PubMed )
Supplement: 41598_2023_39608_MOESM6_ESM.xlsx › Sheet1

Aberrant somatic hypermutation of CCND1 generates non-coding drivers of mantle cell lymphomagenesis.

Müller H et al.

Cancer Gene Therapy, 2022

Mantle cell lymphoma in 2022-A comprehensive update on molecular pathogenesis, risk stratification, clinical approach, and current and novel treatments.

Jain P et al.

American Journal of Hematology, 2022

Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Hescheler DA et al.

Frontiers in Endocrinology, 2021

34630336 (PubMed )
Supplement: Table_1.xlsx › Tab2

Targeted mutation detection in breast cancer using MammaSeq™.

Smith NG et al.

Breast Cancer Research : Bcr, 2019

30736836 (PubMed )
Supplement: 13058_2019_1102_MOESM2_ESM.xlsx › Sheet1

Oncogenic c-terminal cyclin D1 (CCND1) mutations are enriched in endometrioid endometrial adenocarcinomas.

Xu J et al.

Plos One, 2018

A lowered 26S proteasome activity correlates with mantle lymphoma cell lines resistance to genotoxic stress.

Ben Younes K et al.

Bmc Cancer, 2017

CCND1 mutations increase protein stability and promote ibrutinib resistance in mantle cell lymphoma.

Mohanty A et al.

Oncotarget, 2016

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

Chang MT et al.

Nature Biotechnology, 2016

APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma.

Walker BA et al.

Nature Communications, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."