Varaico: Literature-Extracted Genetic Variants

Gene:CCND1
Variant:p.V290V
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CCND1

NM_053056.3:p.V290V

Associated Papers

Structural pharmacogenomics of drug-associated SNPs in oral squamous cell carcinoma.

Sunil P et al.

Frontiers in Genetics, 2026

Genetic variants affecting RNA stability influence complex traits and disease risk.

Huang E et al.

Nature Genetics, 2025

40913182 (PubMed )
Supplement: 41588_2025_2326_MOESM3_ESM.xlsx › Table_S7a

Pathogenic germline variants in small cell lung cancer: A systematic review and meta-analysis.

Ul Haq S et al.

Hgg Advances, 2025

40308030 (PubMed )
Supplement: mmc2.xlsx › Table_S3

Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways.

Bradley J et al.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2025

40556318 (PubMed )
Supplement: ALZ-21-e70377-s001.xlsx › S18-GWAS_CATALOG_PRIORITIZED

Genetic alterations of Cyclin D-CDK4/6-INK4-RB pathway in prostate cancer.

Sivoňová MK et al.

Molecular Biology Reports, 2025

Genome-wide association study and multi-ancestry meta-analysis identify common variants associated with carotid artery intima-media thickness.

Meena D et al.

Medrxiv : the Preprint Server for Health Sciences, 2025

40321265 (PubMed )
Supplement: media-3.xlsx › ST15

Functional variant rs9344 at 11q13.3 regulates CCND1 expression in multiple myeloma with t(11;14).

Tang H et al.

Leukemia, 2025

Breast cancer susceptibility is associated with Cyclin D1 single nucleotide polymorphisms in Iran: A case-control study.

Soleimani S et al.

Molecular Biology Research Communications, 2025

Understanding variants of unknown significance: the computational frontier.

Fu X et al.

The Oncologist, 2024

Integrating leiomyoma genetics, epigenomics, and single-cell transcriptomics reveals causal genetic variants, genes, and cell types.

Buyukcelebi K et al.

Nature Communications, 2024

38326302 (PubMed )
Supplement: 41467_2024_45382_MOESM4_ESM.xlsx › GWAS_catalog

Prostate cancer genetic risk and associated aggressive disease in men of African ancestry.

Soh PXY et al.

Nature Communications, 2023

38052806 (PubMed )
Supplement: 41467_2023_43726_MOESM9_ESM.xlsx › Sheet1

Sonic hedgehog signaling: Alternative splicing and pathogenic role in medulloblastoma.

Qu M et al.

Genes & Diseases, 2023

D-Type Cyclins in Development and Disease.

Saleban M et al.

Genes, 2023

Aberrant Cyclin D1 splicing in cancer: from molecular mechanism to therapeutic modulation.

Wang J et al.

Cell Death & Disease, 2023

Influence of cyclin D1 splicing variants expression on breast cancer chemoresistance via CDK4/CyclinD1-pRB-E2F1 pathway.

Wang J et al.

Journal of Cellular and Molecular Medicine, 2023

Meta-Analysis of 49 SNPs Covering 25,446 Cases and 41,106 Controls Identifies Polymorphisms in Hormone Regulation and DNA Repair Genes Associated with Increased Endometrial Cancer Risk.

Das AP et al.

Genes, 2023

Targeted splicing therapy: new strategies for colorectal cancer.

Zheng Y et al.

Frontiers in Oncology, 2023

Current perspectives on interethnic variability in multiple myeloma: Single cell technology, population pharmacogenetics and molecular signal transduction.

Gandhi M et al.

Translational Oncology, 2022

Study of Breast Cancer Resistance Protein ABCG2 C421A Single Nucleotide Polymorphism RS2231142 in Multiple Myeloma.

Abbassy HA et al.

Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion, 2022

G870A Polymorphic Variants of CCND1 Gene and Cyclin D1 Protein Expression as Prognostic Markers in Laryngeal Lesions.

Kowalczyk MM et al.

Diagnostics (basel, Switzerland), 2022

Genetic polymorphism of tumor necrosis factor alpha (TNF-α) and tumor necrosis factor beta (TNF-β) genes and risk of oral pre-cancer and cancer in North Indian population.

Gupta S et al.

Oral and Maxillofacial Surgery, 2022

Functional dissection of inherited non-coding variation influencing multiple myeloma risk.

Ajore R et al.

Nature Communications, 2022

Gene polymorphisms and risk of head and neck squamous cell carcinoma: a systematic review.

Rajabi-Moghaddam M et al.

Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2022

Genetic variants of cell cycle pathway genes are associated with head and neck squamous cell carcinoma in the Chinese population.

Chen M et al.

Carcinogenesis, 2021

Investigation of the Relationship between CMYC Gene Polymorphisms and Glioma Susceptibility in Chinese Children.

Lou S et al.

Cancer Investigation, 2021

Significant Association of CCND1 Genotypes With Susceptibility to Childhood Acute Lymphoblastic Leukemia.

Hsu PC et al.

Anticancer Research, 2021

The Investigation of Associations between TP53 rs1042522, BBC3 rs2032809, CCND1 rs9344, EGFR rs2227983 Polymorphisms and Breast Cancer Phenotype and Prognosis.

Bekampytė J et al.

Diagnostics (basel, Switzerland), 2021

Sequencing at lymphoid neoplasm susceptibility loci maps six myeloma risk genes.

Waller RG et al.

Human Molecular Genetics, 2021

Crosstalk of Cyclin-dependent kinase inhibitor 1A (CDKN1A) gene polymorphism with p53 and CCND1 polymorphism in breast cancer.

Akhter N et al.

European Review for Medical and Pharmacological Sciences, 2021

Germline variants at SOHLH2 influence multiple myeloma risk.

Duran-Lozano L et al.

Blood Cancer Journal, 2021

33875642 (PubMed )
Supplement: 41408_2021_468_MOESM2_ESM.pdf

Computational analysis of Cyclin D1 gene SNPs and association with breast cancer.

Aftab A et al.

Bioscience Reports, 2021

Association between common variants in vitamin D receptor gene and susceptibility to Non-Hodgkin's lymphoma: a case-control study.

Mashhadi MA et al.

Nucleosides, Nucleotides & Nucleic Acids, 2021

Umbrella Review on Associations Between Single Nucleotide Polymorphisms and Lung Cancer Risk.

Li X et al.

Frontiers in Molecular Biosciences, 2021

34540891 (PubMed )
Supplement: DataSheet1.zip › Data_Sheet_---Supplementary_Additional_file › Supplementary_Additional_file › Supplementary_Additional_file_S2.docx

Redundant meta-analyses are common in genetic epidemiology.

Sigurdson MK et al.

Journal of Clinical Epidemiology, 2020

Cyclin D1 G870A Polymorphism: Relation to the Risk of ALL Development, Prognosis Impact, and Methotrexate Cytotoxicity.

El Menshawy N et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2020

A Scoping Review of Interactions between Omega-3 Long-Chain Polyunsaturated Fatty Acids and Genetic Variation in Relation to Cancer Risk.

Yurko-Mauro K et al.

Nutrients, 2020

Genetic and expression variations of cell cycle pathway genes in brain tumor patients.

Naqvi AZ et al.

Bioscience Reports, 2020

Cumulative Evidence for Associations between Genetic Variants and Risk of Esophageal Cancer.

Li G et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2020

31969372 (PubMed )
Supplement: 10559965epi191281-sup-230715_3_supp_6000458_q3kstt.docx

The CCND1 c.870G risk allele is enriched in individuals of African ancestry with plasma cell dyscrasias.

Baughn LB et al.

Blood Cancer Journal, 2020

Genetic predisposition for multiple myeloma.

Pertesi M et al.

Leukemia, 2020

Association between Single Nucleotide Polymorphisms and Glioma Risk: A Systematic Literature Review.

Tavares CB et al.

Cancer Investigation, 2020

The double dealing of cyclin D1.

Tchakarska G et al.

Cell Cycle (georgetown, Tex.), 2020

Individual and combined effects of GSTM1, GSTT1, and GSTP1 polymorphisms on breast cancer risk: A meta-analysis and re-analysis of systematic meta-analyses.

Miao LF et al.

Plos One, 2020

32155154 (PubMed )
Supplement: pone.0216147.s032.pdf

Implementation of Pharmacogenetics to Individualize Treatment Regimens for Children with Acute Lymphoblastic Leukemia.

Maamari D et al.

Pharmacogenomics and Personalized Medicine, 2020

The Role of Single-Nucleotide Polymorphisms in Pituitary Adenomas Tumorigenesis.

Shah SS et al.

Cancers, 2019

Altered RNA Processing in Cancer Pathogenesis and Therapy.

Obeng EA et al.

Cancer Discovery, 2019

AA genotype of cyclin D1 G870A polymorphism increases breast cancer risk: Findings of a case-control study and meta-analysis.

Akhter N et al.

Journal of Cellular Biochemistry, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."