Varaico: Literature-Extracted Genetic Variants

Gene:CCNH
Variant:p.V270A
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CCNH

NM_001239.4:p.V270A

Associated Papers

Integrative Computational Analysis of Common EXO5 Haplotypes: Impact on Protein Dynamics, Genome Stability, and Cancer Progression.

Mazza F et al.

Journal of Chemical Information and Modeling, 2025

40115981 (PubMed )
Supplement: ci5c00067_si_002.xlsx › scored_ALL_haplotypes_1MAF_cano

Genetic polymorphisms and platinum-induced hematological toxicity: a systematic review.

Zheng Y et al.

Frontiers in Pharmacology, 2024

Pharmacovariome scanning using whole pharmacogene resequencing coupled with deep computational analysis and machine learning for clinical pharmacogenomics.

Tafazoli A et al.

Human Genomics, 2023

Comparative analysis of histopathological parameters, genome-wide copy number alterations, and variants in genes involved in cell cycle regulation in chordomas of the skull base and sacrum.

Salle H et al.

Journal of Neuropathology and Experimental Neurology, 2023

The current state of genetic risk models for the development of kidney cancer: a review and validation.

Harrison H et al.

Bju International, 2022

35460182 (PubMed )
Supplement: BJU-130-550-s004.pdf

Haplotypes of single cancer driver genes and their local ancestry in a highly admixed long-lived population of Northeast Brazil.

Galisa SLG et al.

Genetics and Molecular Biology, 2022

35112701 (PubMed )
Supplement: 1415-4757-GMB-45-1-e20210172-s4.pdf

Polymorphisms in ERCC4 and ERCC5 and risk of cancers: Systematic research synopsis, meta-analysis, and epidemiological evidence.

Zuo C et al.

Frontiers in Oncology, 2022

36033436 (PubMed )
Supplement: Table_3.pdf

Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer.

Liu S et al.

Communications Biology, 2021

33907296 (PubMed )
Supplement: 42003_2021_2024_MOESM11_ESM.xlsx › Supplementary_Data_8

Somatic mutations in the DNA repairome in prostate cancers in African Americans and Caucasians.

Yadav S et al.

Oncogene, 2020

32300177 (PubMed )
Supplement: 41388_2020_1280_MOESM3_ESM.xlsx › Main_Sheet_

Dissecting Mechanisms of Melanoma Resistance to BRAF and MEK Inhibitors Revealed Genetic and Non-Genetic Patient- and Drug-Specific Alterations and Remarkable Phenotypic Plasticity.

Hartman ML et al.

Cells, 2020

31936151 (PubMed )
Supplement: cells-09-00142-s001.pdf

Thyroid Cancer: The Quest for Genetic Susceptibility Involving DNA Repair Genes.

Santos LS et al.

Genes, 2019

Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families.

Shahi RB et al.

Bmc Cancer, 2019

30947698 (PubMed )
Supplement: 12885_2019_5494_MOESM10_ESM.docx

Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione.

Kürschner G et al.

Oncotarget, 2017

29285300 (PubMed )
Supplement: oncotarget-08-105882-s002.xlsx › nuclear_gene_mutations

A case-control study on association of nucleotide excision repair polymorphisms and its interaction with environment factors with the susceptibility to non-melanoma skin cancer.

Li YL et al.

Oncotarget, 2017

The role of CCNH Val270Ala (rs2230641) and other nucleotide excision repair polymorphisms in individual susceptibility to well-differentiated thyroid cancer.

Santos LS et al.

Oncology Reports, 2013

The impact of pharmacogenetics on radiation therapy outcome in cancer patients. A focus on DNA damage response genes.

Borchiellini D et al.

Cancer Treatment Reviews, 2012

hOGG1 Ser326Cys polymorphism is associated with risk of bladder cancer in a Chinese population: a case-control study.

Ma L et al.

Cancer Science, 2012

Association between polymorphisms of DNA repair genes and survival of advanced NSCLC patients treated with platinum-based chemotherapy.

Ren S et al.

Lung Cancer (amsterdam, Netherlands), 2012

Association between single nucleotide polymorphisms (SNPs) and toxicity of advanced non-small-cell lung cancer patients treated with chemotherapy.

Zhang L et al.

Plos One, 2012

Genetic variation in radiation and platinum pathways predicts severe acute radiation toxicity in patients with esophageal adenocarcinoma treated with cisplatin-based preoperative radiochemotherapy: results from the Eastern Cooperative Oncology Group.

Yoon HH et al.

Cancer Chemotherapy and Pharmacology, 2011

Acute myeloid leukemia outcome: role of nucleotide excision repair polymorphisms in intermediate risk patients.

Strom SS et al.

Leukemia & Lymphoma, 2010

Genetic susceptibility to esophageal cancer: the role of the nucleotide excision repair pathway.

Pan J et al.

Carcinogenesis, 2009

Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.

Enjuanes A et al.

Cancer Research, 2008

Case-control analysis of nucleotide excision repair pathway and the risk of renal cell carcinoma.

Lin J et al.

Carcinogenesis, 2008

Genetic susceptibility to bladder cancer with an emphasis on gene-gene and gene-environmental interactions.

Horikawa Y et al.

Current Opinion in Urology, 2008

Genotyping panel for assessing response to cancer chemotherapy.

Dai Z et al.

Bmc Medical Genomics, 2008

18547414 (PubMed )
Supplement: 1755-8794-1-24-S1.xls › SNPs_selected_for_SNPlex_design

High-order interactions among genetic polymorphisms in nucleotide excision repair pathway genes and smoking in modulating bladder cancer risk.

Chen M et al.

Carcinogenesis, 2007

Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation.

Lin J et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2007

Polymorphisms in apoptosis and cell cycle control genes and risk of brain tumors in adults.

Rajaraman P et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2007

Nucleotide excision repair pathway genes and oral premalignant lesions.

Wang Y et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2007

Nucleotide excision repair gene polymorphisms and risk of advanced colorectal adenoma: XPC polymorphisms modify smoking-related risk.

Huang WY et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2006

A database of single-nucleotide polymorphisms and a genotyping microarray for genetic epidemiology of lung cancer.

Landi S et al.

Experimental Lung Research, 2005

Sporadic colorectal cancer and individual susceptibility: a review of the association studies investigating the role of DNA repair genetic polymorphisms.

Naccarati A et al.

Mutation Research, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."