Varaico: Literature-Extracted Genetic Variants

Gene:CCR4
Variant:p.Y331*
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CCR4

NM_005508.5:p.Y331*

Associated Papers

Mechanisms of action and resistance in histone methylation-targeted therapy.

Yamagishi M et al.

Nature, 2024

38383791 (PubMed )
Supplement: 41586_2024_7103_MOESM3_ESM.xlsx › Sup_Table_4

CCR7 alterations associated with inferior outcome of adult T-cell leukemia/lymphoma under mogamulizumab treatment.

Sakamoto Y et al.

Hematological Oncology, 2022

Clinical significance of TP53 mutations in adult T-cell leukemia/lymphoma.

Sakamoto Y et al.

British Journal of Haematology, 2021

Genetic profile of adult T-cell leukemia/lymphoma in Okinawa: Association with prognosis, ethnicity, and HTLV-1 strains.

Sakihama S et al.

Cancer Science, 2021

33426772 (PubMed )
Supplement: CAS-112-1300-s002.xlsx › Table_S4

Immunohistochemistry for CCR4 C-terminus predicts CCR4 mutations and mogamulizumab efficacy in adult T-cell leukemia/lymphoma.

Fujii K et al.

The Journal of Pathology. Clinical Research, 2021

cDNA-Based Mutation Screening Using a Combination of High-Resolution Melting Curve and Fragment Analysis Facilitates Efficient CCR4 Mutation Analysis in Adult T-Cell Leukemia/Lymphoma.

Mizuta S et al.

American Journal of Clinical Pathology, 2020

Overlap at the molecular and immunohistochemical levels between angioimmunoblastic T-cell lymphoma and a subgroup of peripheral T-cell lymphomas without specific morphological features.

Manso R et al.

Oncotarget, 2018

29662631 (PubMed )
Supplement: oncotarget-09-16124-s002.xls › Supplementary_Table_3

CCR4 frameshift mutation identifies a distinct group of adult T cell leukaemia/lymphoma with poor prognosis.

Yoshida N et al.

The Journal of Pathology, 2016

Genomic profiling of Sézary syndrome identifies alterations of key T cell signaling and differentiation genes.

Wang L et al.

Nature Genetics, 2015

Integrated molecular analysis of adult T cell leukemia/lymphoma.

Kataoka K et al.

Nature Genetics, 2015

Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma.

Nakagawa M et al.

The Journal of Experimental Medicine, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."