Varaico: Literature-Extracted Genetic Variants

Gene:CCR5
Variant:p.L55Q
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CCR5

NM_001394783.1:p.L55Q

Associated Papers

Next-generation sequencing of CCR5, CXCR4, and IFNAR1 variants in relation to HIV-1 disease progression and ART response.

Pekkoc-Uyanik KC et al.

Scientific Reports, 2025

Myeloid lineage cells evince distinct steady-state level of certain gene groups in dependence on hereditary angioedema severity.

Ballonová L et al.

Frontiers in Genetics, 2023

37470035 (PubMed )
Supplement: Table1.XLSX › Table_S3_Deleterious_gene_varia

Optimisation of a TALE nuclease targeting the HIV co-receptor CCR5 for clinical application.

Schwarze LI et al.

Gene Therapy, 2021

Genetic Polymorphisms in the Open Reading Frame of the CCR5 gene From HIV-1 Seronegative and Seropositive Individuals From National Capital Regions of India.

Ronsard L et al.

Scientific Reports, 2019

Association of Diverse Genotypes and Phenotypes of Immune Cells and Immunoglobulins With the Course of HIV-1 Infection.

Li L et al.

Frontiers in Immunology, 2018

Amino- and Carboxyl-Terminal CCR5 Mutations in Brazilian HIV-1-Infected Women and Homology Model of p.L55Q CCR5 Mutant.

Costa GC et al.

Aids Research and Human Retroviruses, 2015

XomAnnotate: Analysis of Heterogeneous and Complex Exome- A Step towards Translational Medicine.

Talukder AK et al.

Plos One, 2015

25905921 (PubMed )
Supplement: pone.0123569.s008.xls › BC1_ERR166303

Mutations in C-C chemokine receptor type 5 (CCR5) in South African individuals.

Barmania F et al.

International Journal of Infectious Diseases : Ijid : Official Publication of the International Society for Infectious Diseases, 2013

Structure-function studies on non-synonymous SNPs of chemokine receptor gene implicated in cardiovascular disease: a computational approach.

Sai Ramesh A et al.

The Protein Journal, 2013

Determination of the CCR5∆32 frequency in Emiratis and Tunisians and the screening of the CCR5 gene for novel alleles in Emiratis.

Al-Jaberi SA et al.

Gene, 2013

Distribution of the CCR5delta32 allele (gene variant CCR5) in Rondônia, Western Amazonian region, Brazil.

de Farias JD et al.

Genetics and Molecular Biology, 2012

Analysis of the CCR5 gene coding region diversity in five South American populations reveals two new non-synonymous alleles in Amerindians and high CCR5*D32 frequency in Euro-Brazilians.

Boldt AB et al.

Genetics and Molecular Biology, 2009

Identification of the CCR5-Delta32 HIV resistance allele and new mutations of the CCR5 gene in different Tunisian populations.

Jlizi A et al.

Human Immunology, 2007

A novel 24-base pair deletion in the coding region of CCR5 in an African population.

Masquelier C et al.

Aids (london, England), 2007

Inactivating mutations of G protein-coupled receptors and diseases: structure-function insights and therapeutic implications.

Tao YX

Pharmacology & Therapeutics, 2006

Variants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5.

Dong HF et al.

Genes and Immunity, 2005

Haplotype structure and linkage disequilibrium in chemokine and chemokine receptor genes.

Clark VJ et al.

Human Genomics, 2004

The differential sensitivity of human and rhesus macaque CCR5 to small-molecule inhibitors of human immunodeficiency virus type 1 entry is explained by a single amino acid difference and suggests a mechanism of action for these inhibitors.

Billick E et al.

Journal of Virology, 2004

Characterisation of SNP haplotype structure in chemokine and chemokine receptor genes using CEPH pedigrees and statistical estimation.

Clark VJ et al.

Human Genomics, 2004

Polymorphisms in the CCR5 coding and noncoding regions among HIV type 1-exposed, persistently seronegative female sex-workers from Thailand.

Yang C et al.

Aids Research and Human Retroviruses, 2003

Statistical estimation and pedigree analysis of CCR2-CCR5 haplotypes.

Clark VJ et al.

Human Genetics, 2001

Novel mutations identified using a comprehensive CCR5-denaturing gradient gel electrophoresis assay.

Petersen DC et al.

Aids (london, England), 2001

Multiple nonfunctional alleles of CCR5 are frequent in various human populations.

Blanpain C et al.

Blood, 2000

Sequence evolution of the CCR5 chemokine receptor gene in primates.

Zhang YW et al.

Molecular Biology and Evolution, 1999

Naturally occurring CCR5 extracellular and transmembrane domain variants affect HIV-1 Co-receptor and ligand binding function.

Howard OM et al.

The Journal of Biological Chemistry, 1999

Genetics of HIV-1 infection: chemokine receptor CCR5 polymorphism and its consequences.

Carrington M et al.

Human Molecular Genetics, 1999

Novel alleles of the chemokine-receptor gene CCR5.

Carrington M et al.

American Journal of Human Genetics, 1997

Association of the CCR5Δ32 Mutant Genotype with Sickle Cell Disease in Egyptian Patients.

El Sissy MH et al.

Hemoglobin, 0

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