Varaico: Literature-Extracted Genetic Variants

Gene:CCR5
Variant:p.V130I
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CCR5

NM_001394783.1:p.V130I

Associated Papers

Structural insight into a novel human CCR5-V130I variant associated with resistance to HIV-1 infection.

Stambouli N et al.

Journal of Biomolecular Structure & Dynamics, 2014

Structural basis for the interaction of CCR5 with a small molecule, functionally selective CCR5 agonist.

Saita Y et al.

Journal of Immunology (baltimore, Md. : 1950), 2006

The differential sensitivity of human and rhesus macaque CCR5 to small-molecule inhibitors of human immunodeficiency virus type 1 entry is explained by a single amino acid difference and suggests a mechanism of action for these inhibitors.

Billick E et al.

Journal of Virology, 2004

Parallel evolution of CCR5-null phenotypes in humans and in a natural host of simian immunodeficiency virus.

Palacios E et al.

Current Biology : Cb, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."