Varaico: Literature-Extracted Genetic Variants

Gene:CCR5
Variant:p.K171R
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CCR5

NM_001394783.1:p.K171R

Associated Papers

Species-Specific Valid Ternary Interactions of HIV-1 Env-gp120, CD4, and CCR5 as Revealed by an Adaptive Single-Amino Acid Substitution at the V3 Loop Tip.

Koma T et al.

Journal of Virology, 2021

Structural basis for the interaction of CCR5 with a small molecule, functionally selective CCR5 agonist.

Saita Y et al.

Journal of Immunology (baltimore, Md. : 1950), 2006

The differential sensitivity of human and rhesus macaque CCR5 to small-molecule inhibitors of human immunodeficiency virus type 1 entry is explained by a single amino acid difference and suggests a mechanism of action for these inhibitors.

Billick E et al.

Journal of Virology, 2004

A critical site in the core of the CCR5 chemokine receptor required for binding and infectivity of human immunodeficiency virus type 1.

Siciliano SJ et al.

The Journal of Biological Chemistry, 1999

Parallel evolution of CCR5-null phenotypes in humans and in a natural host of simian immunodeficiency virus.

Palacios E et al.

Current Biology : Cb, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."