Varaico: Literature-Extracted Genetic Variants

Gene:CCR5
Variant:p.C178R
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CCR5

NM_001394783.1:p.C178R

Associated Papers

Resistance to Human Immunodeficiency Virus 1 Infection Conferred by a Compound CCR5Δ32 and CCR5 C20S Heterozygote.

Alkhatib B et al.

The Journal of Infectious Diseases, 2023

Convergent transcriptomic and genomic evidence supporting a dysregulation of CXCL16 and CCL5 in Alzheimer's disease.

Li X et al.

Alzheimer's Research & Therapy, 2023

36670424 (PubMed )
Supplement: 13195_2022_1159_MOESM2_ESM.xlsx › rare_variants

Genetic Polymorphisms in the Open Reading Frame of the CCR5 gene From HIV-1 Seronegative and Seropositive Individuals From National Capital Regions of India.

Ronsard L et al.

Scientific Reports, 2019

Association of Diverse Genotypes and Phenotypes of Immune Cells and Immunoglobulins With the Course of HIV-1 Infection.

Li L et al.

Frontiers in Immunology, 2018

Structure-function studies on non-synonymous SNPs of chemokine receptor gene implicated in cardiovascular disease: a computational approach.

Sai Ramesh A et al.

The Protein Journal, 2013

Determination of the CCR5∆32 frequency in Emiratis and Tunisians and the screening of the CCR5 gene for novel alleles in Emiratis.

Al-Jaberi SA et al.

Gene, 2013

HIV type 1 coreceptor tropism, CCR5 genotype, and integrase inhibitor resistance profiles in Vietnam: implications for the introduction of new antiretroviral regimens.

Luu QP et al.

Aids Research and Human Retroviruses, 2012

Identification of the CCR5-Delta32 HIV resistance allele and new mutations of the CCR5 gene in different Tunisian populations.

Jlizi A et al.

Human Immunology, 2007

A novel 24-base pair deletion in the coding region of CCR5 in an African population.

Masquelier C et al.

Aids (london, England), 2007

Genetics of resistance to HIV infection: Role of co-receptors and co-receptor ligands.

Arenzana-Seisdedos F et al.

Seminars in Immunology, 2006

Inactivating mutations of G protein-coupled receptors and diseases: structure-function insights and therapeutic implications.

Tao YX

Pharmacology & Therapeutics, 2006

[Single nucleotide polymorphisms of HIV coreceptor CCR5 gene in Chinese Yi ethnic group and its association with HIV infection].

Ma LY et al.

Zhonghua Yi Xue Za Zhi, 2005

Biochemical and HIV-1 coreceptor properties of K26R, a new CCR5 Variant in China's Sichuan population.

Ma L et al.

Journal of Acquired Immune Deficiency Syndromes (1999), 2005

New CCR5 variants associated with reduced HIV coreceptor function in southeast Asia.

Capoulade-Métay C et al.

Aids (london, England), 2004

The differential sensitivity of human and rhesus macaque CCR5 to small-molecule inhibitors of human immunodeficiency virus type 1 entry is explained by a single amino acid difference and suggests a mechanism of action for these inhibitors.

Billick E et al.

Journal of Virology, 2004

Polymorphisms in the CCR5 coding and noncoding regions among HIV type 1-exposed, persistently seronegative female sex-workers from Thailand.

Yang C et al.

Aids Research and Human Retroviruses, 2003

Multiple nonfunctional alleles of CCR5 are frequent in various human populations.

Blanpain C et al.

Blood, 2000

Novel variant of the CCR5 gene in a Vietnamese population.

Magierowska M et al.

Microbes and Infection, 1999

[Pharmacological chaperones: a potential therapeutic treatment for conformational diseases].

Mendre C et al.

Medecine Sciences : M/s, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."