Varaico: Literature-Extracted Genetic Variants

Gene:CCR5
Variant:p.S180P
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CCR5

NM_001394783.1:p.S180P

Associated Papers

Allosteric model of maraviroc binding to CC chemokine receptor 5 (CCR5).

Garcia-Perez J et al.

The Journal of Biological Chemistry, 2011

Molecular anatomy of CCR5 engagement by physiologic and viral chemokines and HIV-1 envelope glycoproteins: differences in primary structural requirements for RANTES, MIP-1 alpha, and vMIP-II Binding.

Navenot JM et al.

Journal of Molecular Biology, 2001

CCR5-Mediated human immunodeficiency virus entry depends on an amino-terminal gp120-binding site and on the conformational integrity of all four extracellular domains.

Genoud S et al.

Journal of Virology, 1999

Parallel evolution of CCR5-null phenotypes in humans and in a natural host of simian immunodeficiency virus.

Palacios E et al.

Current Biology : Cb, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."