Associated Papers
A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands.
Swinney DC et al.
British Journal of Pharmacology, 2014
Allosteric model of maraviroc binding to CC chemokine receptor 5 (CCR5).
Garcia-Perez J et al.
The Journal of Biological Chemistry, 2011
Two HIV-1 variants resistant to small molecule CCR5 inhibitors differ in how they use CCR5 for entry.
Berro R et al.
Plos Pathogens, 2009
Involvement of the second extracellular loop and transmembrane residues of CCR5 in inhibitor binding and HIV-1 fusion: insights into the mechanism of allosteric inhibition.
Maeda K et al.
Journal of Molecular Biology, 2008
Structural and molecular interactions of CCR5 inhibitors with CCR5.
Maeda K et al.
The Journal of Biological Chemistry, 2006
Substitutions in a homologous region of extracellular loop 2 of CXCR4 and CCR5 alter coreceptor activities for HIV-1 membrane fusion and virus entry.
Chabot DJ et al.
The Journal of Biological Chemistry, 2000
CCR5-Mediated human immunodeficiency virus entry depends on an amino-terminal gp120-binding site and on the conformational integrity of all four extracellular domains.
Genoud S et al.
Journal of Virology, 1999
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