Varaico: Literature-Extracted Genetic Variants

Gene:CCR5
Variant:p.D276A
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CCR5

NM_001394783.1:p.D276A

Associated Papers

Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5).

Karlshøj S et al.

The Journal of Biological Chemistry, 2016

Elucidating a key anti-HIV-1 and cancer-associated axis: the structure of CCL5 (Rantes) in complex with CCR5.

Tamamis P et al.

Scientific Reports, 2014

Contrasting use of CCR5 structural determinants by R5 and R5X4 variants within a human immunodeficiency virus type 1 primary isolate quasispecies.

Yi Y et al.

Journal of Virology, 2003

The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle.

Blanpain C et al.

The Journal of Biological Chemistry, 2003

Molecular anatomy of CCR5 engagement by physiologic and viral chemokines and HIV-1 envelope glycoproteins: differences in primary structural requirements for RANTES, MIP-1 alpha, and vMIP-II Binding.

Navenot JM et al.

Journal of Molecular Biology, 2001

CCR5-Mediated human immunodeficiency virus entry depends on an amino-terminal gp120-binding site and on the conformational integrity of all four extracellular domains.

Genoud S et al.

Journal of Virology, 1999

Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry.

Dragic T et al.

Journal of Virology, 1998

Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1.

Doranz BJ et al.

Journal of Virology, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."