Varaico: Literature-Extracted Genetic Variants

Gene:CCR5
Variant:p.A335V
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CCR5

NM_001394783.1:p.A335V

Associated Papers

Accurate affinity models for SH2 domains from peptide binding assays and free-energy regression.

Gagoski D et al.

Protein Science : a Publication of the Protein Society, 2025

41088778 (PubMed )
Supplement: PRO-34-e70317-s008.xlsx › _S6_-_PTMVar_-_Fyn

Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression.

Gagoski D et al.

Biorxiv : the Preprint Server for Biology, 2025

39764007 (PubMed )
Supplement: media-1.xlsx › _S6_-_PTMVar_-_Fyn

Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry.

Claireaux M et al.

Nature Communications, 2022

Lysine acetylation regulates the interaction between proteins and membranes.

Okada AK et al.

Nature Communications, 2021

34753925 (PubMed )
Supplement: 41467_2021_26657_MOESM4_ESM.zip › Bioinformatics.zip › Datasets › Unused › PTMVAR_download.xlsx › Humsavar_overlap_2PSP_PTM5-14-1

Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.

Zhou Y et al.

Science Advances, 2021

34516913 (PubMed )
Supplement: sciadv.abi6856_tables_s1_to_s8.zip › sciadv.abi6856_Table_S6.xlsx › Sheet1

Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Holehouse AS et al.

Plos One, 2015

26659599 (PubMed )
Supplement: pone.0144692.s002.xlsx › suppTable_2.txt

Mutations in C-C chemokine receptor type 5 (CCR5) in South African individuals.

Barmania F et al.

International Journal of Infectious Diseases : Ijid : Official Publication of the International Society for Infectious Diseases, 2013

Genetic variation within the gene encoding the HIV-1 CCR5 coreceptor in two South African populations.

Picton AC et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2010

Analysis of the CCR5 gene coding region diversity in five South American populations reveals two new non-synonymous alleles in Amerindians and high CCR5*D32 frequency in Euro-Brazilians.

Boldt AB et al.

Genetics and Molecular Biology, 2009

Identification of the CCR5-Delta32 HIV resistance allele and new mutations of the CCR5 gene in different Tunisian populations.

Jlizi A et al.

Human Immunology, 2007

A novel 24-base pair deletion in the coding region of CCR5 in an African population.

Masquelier C et al.

Aids (london, England), 2007

Genetics of resistance to HIV infection: Role of co-receptors and co-receptor ligands.

Arenzana-Seisdedos F et al.

Seminars in Immunology, 2006

Inactivating mutations of G protein-coupled receptors and diseases: structure-function insights and therapeutic implications.

Tao YX

Pharmacology & Therapeutics, 2006

Variants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5.

Dong HF et al.

Genes and Immunity, 2005

Are polymorphic markers within the alpha-1-antitrypsin gene associated with risk of human immunodeficiency virus disease?

Hayes VM et al.

The Journal of Infectious Diseases, 2003

African-based CCR5 single-nucleotide polymorphism associated with HIV-1 disease progression.

Hayes VM et al.

Aids (london, England), 2002

Novel mutations identified using a comprehensive CCR5-denaturing gradient gel electrophoresis assay.

Petersen DC et al.

Aids (london, England), 2001

Multiple nonfunctional alleles of CCR5 are frequent in various human populations.

Blanpain C et al.

Blood, 2000

Genetics of HIV-1 infection: chemokine receptor CCR5 polymorphism and its consequences.

Carrington M et al.

Human Molecular Genetics, 1999

Novel alleles of the chemokine-receptor gene CCR5.

Carrington M et al.

American Journal of Human Genetics, 1997

Association of the CCR5Δ32 Mutant Genotype with Sickle Cell Disease in Egyptian Patients.

El Sissy MH et al.

Hemoglobin, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."