Varaico: Literature-Extracted Genetic Variants

Gene:CD28
Variant:p.S26W
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CD28

NM_006139.4:p.S26W

Associated Papers

C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease.

Landskron J et al.

Plos One, 2017

Overexpression of CD45RA isoforms in carriers of the C77G mutation leads to hyporeactivity of CD4+CD25highFoxp3+ regulatory T cells.

Pokoyski C et al.

Genes and Immunity, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."