Varaico: Literature-Extracted Genetic Variants

Gene:CDC20
Variant:p.Y228C
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CDC20

NM_001255.3:p.Y228C

Associated Papers

Genetic landscape of human oocyte/embryo defects.

Chen B et al.

Cell Genomics, 2026

41005306 (PubMed )
Supplement: mmc3.xlsx › Table_S2

Biallelic mutations in CDC20 cause female infertility due to oocyte maturation abnormality.

Jiao G et al.

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology, 2025

Advances in monogenic female infertility.

Gu H et al.

Journal of Genetics and Genomics = Yi Chuan Xue Bao, 2025

Targeting G1-S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors.

Singh S et al.

Nature, 2025

40836083 (PubMed )
Supplement: 41586_2025_9433_MOESM4_ESM.zip › 2024-07-15654B-s4 › Table_S5_052925.xlsx › Tab_5-zscore_CDC20_A_G

Two Novel Protein-Truncating Variants in NLRP2 and Their Functional Impacts on the Subcortical Maternal Complex.

Yalcin Z et al.

Clinical Genetics, 2025

39905760 (PubMed )
Supplement: CGE-108-179-s003.docx

Exonic genetic variants associated with unexpected fertilization failure and zygotic arrest after ICSI: a systematic review.

Torra-Massana M et al.

Zygote (cambridge, England), 2023

Genetic variants underlying developmental arrests in human preimplantation embryos.

Ozturk S

Molecular Human Reproduction, 2023

Germline Missense Variants in CDC20 Result in Aberrant Mitotic Progression and Familial Cancer.

Chen OJ et al.

Cancer Research, 2022

Gene mutations impede oocyte maturation, fertilization, and early embryonic development.

Fei CF et al.

Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology, 2022

The homozygous p.Tyr228Cys variant in CDC20 causes oocyte maturation arrest: an additional evidence supporting the causality between CDC20 mutation and female infertility.

Xu Y et al.

Journal of Assisted Reproduction and Genetics, 2021

Novel Mutations in CDC20 Are Associated with Female Infertility Due to Oocyte Maturation Abnormality and Early Embryonic Arrest.

Huang L et al.

Reproductive Sciences (thousand Oaks, Calif.), 2021

Identification of Novel Mutations in CDC20: Expanding the Mutational Spectrum for Female Infertility.

Zhao L et al.

Frontiers in Cell and Developmental Biology, 2021

Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development.

Zhao L et al.

Protein & Cell, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."