Associated Papers
A Comparative Genomic Analysis of Parathyroid Adenomas and Carcinomas Harboring Heterozygous Germline CDC73 Mutations.
Li Y et al.
The Journal of Clinical Endocrinology and Metabolism, 2025
Insights into Hyperparathyroidism-Jaw Tumour Syndrome: From Endocrine Acumen to the Spectrum of CDC73 Gene and Parafibromin-Deficient Tumours.
Gheorghe AM et al.
International Journal of Molecular Sciences, 2024
Phenotypic Profiling and Molecular Mechanisms in Hyperparathyroidism-jaw Tumor Syndrome.
Tora R et al.
The Journal of Clinical Endocrinology and Metabolism, 2023
Genetic Alteration Profiles and Clinicopathological Associations in Atypical Parathyroid Adenoma.
Mao X et al.
International Journal of Genomics, 2021
Genetic profiling as a clinical tool in advanced parathyroid carcinoma.
Kutahyalioglu M et al.
Journal of Cancer Research and Clinical Oncology, 2019
Comprehensive Genomic Characterization of Parathyroid Cancer Identifies Novel Candidate Driver Mutations and Core Pathways.
Clarke CN et al.
Journal of the Endocrine Society, 2019
A Young Male with Parafibromin-Deficient Parathyroid Carcinoma Due to a Rare Germline HRPT2/CDC73 Mutation.
Kapur A et al.
Endocrine Pathology, 2018
CDC73-Related Disorders: Clinical Manifestations and Case Detection in Primary Hyperparathyroidism.
van der Tuin K et al.
The Journal of Clinical Endocrinology and Metabolism, 2017
Molecular genetics of syndromic and non-syndromic forms of parathyroid carcinoma.
Cardoso L et al.
Human Mutation, 2017
Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome.
Sun W et al.
Scientific Reports, 2017
Update on parathyroid carcinoma.
Cetani F et al.
Journal of Endocrinological Investigation, 2016
The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination.
Hahn MA et al.
Human Molecular Genetics, 2012
Genome-wide and locus specific alterations in CDC73/HRPT2-mutated parathyroid tumors.
Sulaiman L et al.
Plos One, 2012
Novel nonsense CDC73 mutations in Chinese patients with parathyroid tumors.
Siu WK et al.
Familial Cancer, 2011
Absence of nucleolar parafibromin immunoreactivity in subsets of parathyroid malignant tumours.
Juhlin CC et al.
Virchows Archiv : an International Journal of Pathology, 2011
Identification of de novo germline mutations in the HRPT2 gene in two apparently sporadic cases with challenging parathyroid tumor diagnoses.
Cavaco BM et al.
Endocrine Pathology, 2011
Cell division cycle protein 73 homolog (CDC73) mutations in the hyperparathyroidism-jaw tumor syndrome (HPT-JT) and parathyroid tumors.
Newey PJ et al.
Human Mutation, 2010
The effect of disease-associated HRPT2 mutations on splicing.
Hahn MA et al.
The Journal of Endocrinology, 2009
HRPT2 gene analysis and the diagnosis of parathyroid carcinoma.
Cetani F et al.
Expert Review of Endocrinology & Metabolism, 2008
Molecular diagnosis of primary hyperparathyroidism in familial cancer syndromes.
Marsh DJ et al.
Expert Opinion on Medical Diagnostics, 2007
Identification of a functional bipartite nuclear localization signal in the tumor suppressor parafibromin.
Hahn MA et al.
Oncogene, 2005
Somatic and germ-line mutations of the HRPT2 gene in sporadic parathyroid carcinoma.
Shattuck TM et al.
The New England Journal of Medicine, 2003