Associated Papers
Actomyosin contractility and a threshold of cadherin cell adhesion are required during tissue fusion.
Teng CS et al.
The Journal of Cell Biology, 2026
Proteome-scale characterisation of motif-based interactome rewiring by disease mutations.
Kliche J et al.
Molecular Systems Biology, 2024
The ECM and tissue architecture are major determinants of early invasion mediated by E-cadherin dysfunction.
Melo S et al.
Communications Biology, 2023
vaRHC: an R package for semi-automation of variant classification in hereditary cancer genes according to ACMG/AMP and gene-specific ClinGen guidelines.
Munté E et al.
Bioinformatics (oxford, England), 2023
Development of a Novel NGS Methodology for Ultrasensitive Circulating Tumor DNA Detection as a Tool for Early-Stage Breast Cancer Diagnosis.
Jiménez-Rodríguez B et al.
International Journal of Molecular Sciences, 2022
Mutational landscape of gastric adenocarcinoma in Latin America: A genetic approach for precision medicine.
Cerrato-Izaguirre D et al.
Genes & Diseases, 2022
Differential Impacts on Tensional Homeostasis of Gastric Cancer Cells Due to Distinct Domain Variants of E-Cadherin.
Xu H et al.
Cancers, 2022
Integrin β1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells.
Figueiredo J et al.
Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2022
TUMOSPEC: A Nation-Wide Study of Hereditary Breast and Ovarian Cancer Families with a Predicted Pathogenic Variant Identified through Multigene Panel Testing.
Lesueur F et al.
Cancers, 2021
Rare germline variants in the E-cadherin gene CDH1 are associated with the risk of brain tumors of neuroepithelial and epithelial origin.
Förster A et al.
Acta Neuropathologica, 2021
Geographical Distribution of E-cadherin Germline Mutations in the Context of Diffuse Gastric Cancer: A Systematic Review.
Corso G et al.
Cancers, 2021
Overview on new progress of hereditary diffuse gastric cancer with CDH1 variants.
Hu MN et al.
Tumori, 2020
Gene mutations distinguishing gastric from colorectal and esophageal adenocarcinomas.
Hoang T et al.
Journal of Gastrointestinal Oncology, 2020
Comparative analysis of functional assay evidence use by ClinGen Variant Curation Expert Panels.
Kanavy DM et al.
Genome Medicine, 2019
Frequency of CDH1 germline variants and contribution of dietary habits in early age onset gastric cancer patients in Brazil.
Guindalini RSC et al.
Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2019
Molecular features of premenopausal breast cancers in Latin American women: Pilot results from the PRECAMA study.
Olivier M et al.
Plos One, 2019
Specifications of the ACMG/AMP variant curation guidelines for the analysis of germline CDH1 sequence variants.
Lee K et al.
Human Mutation, 2018
Quantification of topological features in cell meshes to explore E-cadherin dysfunction.
Mestre T et al.
Scientific Reports, 2016
Quantification of mutant E-cadherin using bioimaging analysis of in situ fluorescence microscopy. A new approach to CDH1 missense variants.
Sanches JM et al.
European Journal of Human Genetics : Ejhg, 2015
Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond.
Hansford S et al.
Jama Oncology, 2015
The importance of E-cadherin binding partners to evaluate the pathogenicity of E-cadherin missense mutations associated to HDGC.
Figueiredo J et al.
European Journal of Human Genetics : Ejhg, 2013
Frequency of CDH1 germline mutations in gastric carcinoma coming from high- and low-risk areas: metanalysis and systematic review of the literature.
Corso G et al.
Bmc Cancer, 2012
Evidence that proteosome inhibitors and chemical chaperones can rescue the activity of retinol dehydrogenase 12 mutant T49M.
Lee SA et al.
Chemico-biological Interactions, 2011
ADP-ribosylation factor 6 mediates E-cadherin recovery by chemical chaperones.
Figueiredo J et al.
Plos One, 2011
Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.
Ishiyama N et al.
Cell, 2010
Hereditary diffuse gastric cancer: translation of CDH1 germline mutations into clinical practice.
Guilford P et al.
Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2010
Hereditary diffuse gastric cancer.
Schrader K et al.
Cancer Treatment and Research, 2010
E-cadherin mutations and cell motility: a genotype-phenotype correlation.
Mateus AR et al.
Experimental Cell Research, 2009
Endoplasmic reticulum quality control: a new mechanism of E-cadherin regulation and its implication in cancer.
Simões-Correia J et al.
Human Molecular Genetics, 2008
A short guide to hereditary diffuse gastric cancer.
Guilford P et al.
Hereditary Cancer in Clinical Practice, 2007
Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer.
Kaurah P et al.
Jama, 2007