Varaico: Literature-Extracted Genetic Variants

Gene:CDK1
Variant:p.Y15F
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CDK1

NM_001786.5:p.Y15F

Associated Papers

Phosphorylation of Ephexin4 at Ser-41 contributes to chromosome alignment via RhoG activation in cell division.

Yasutake R et al.

The Journal of Biological Chemistry, 2025

A complex role of Arabidopsis CDKD;3 in meiotic progression and cytokinesis.

Tanasa S et al.

Plant Direct, 2023

ODF2L acts as a synthetic lethal partner with WEE1 inhibition in epithelial ovarian cancer models.

Li J et al.

The Journal of Clinical Investigation, 2023

The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance.

Zhang H et al.

Development (cambridge, England), 2022

Proximity Labeling Reveals Spatial Regulation of the Anaphase-Promoting Complex/Cyclosome by a Microtubule Adaptor.

Cao X et al.

Acs Chemical Biology, 2022

The phosphatase CTDSPL2 is phosphorylated in mitosis and a target for restraining tumor growth and motility in pancreatic cancer.

Xiao Y et al.

Cancer Letters, 2022

EphA2 phosphorylation at Ser897 by the Cdk1/MEK/ERK/RSK pathway regulates M-phase progression via maintenance of cortical rigidity.

Kaibori Y et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2019

Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality.

Szmyd R et al.

Oncogene, 2019

Expression of constitutively active CDK1 stabilizes APC-Cdh1 substrates and potentiates premature spindle assembly and checkpoint function in G1 cells.

Ma Y et al.

Plos One, 2012

Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast.

Rhind N et al.

Genes & Development, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."