Varaico: Literature-Extracted Genetic Variants

Gene:CDK1
Variant:p.D146N
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CDK1

NM_001786.5:p.D146N

Associated Papers

CARM1 S217 phosphorylation by CDK1 in late G2 phase facilitates mitotic entry.

Cho Y et al.

Cell Death & Disease, 2025

Non-catalytic allostery in α-TAT1 by a phospho-switch drives dynamic microtubule acetylation.

Deb Roy A et al.

The Journal of Cell Biology, 2022

Allosteric Regulation of Cyclin-B Binding by the Charge State of Catalytic Lysine in CDK1 Is Essential for Cell-Cycle Progression.

Deota S et al.

Journal of Molecular Biology, 2019

CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma.

Ravindran Menon D et al.

Cancer Research, 2018

CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance.

Liu R et al.

Molecular Cancer Therapeutics, 2015

Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1.

St Gelais C et al.

Journal of Virology, 2014

Role of the p53 family in stabilizing the genome and preventing polyploidization.

Talos F et al.

Advances in Experimental Medicine and Biology, 2010

p73 suppresses polyploidy and aneuploidy in the absence of functional p53.

Talos F et al.

Molecular Cell, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."