Varaico: Literature-Extracted Genetic Variants

Gene:CDK12
Variant:p.S323L
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CDK12

NM_016507.4:p.S323L

Associated Papers

A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC).

Low JL et al.

Ebiomedicine, 2021

33529999 (PubMed )
Supplement: mmc2.xlsx › Table_S2

Genome-based Mutational Analysis by Next Generation Sequencing in Patients with Malignant Pleural and Peritoneal Mesothelioma.

Ugurluer G et al.

Anticancer Research, 2016

Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex.

Ekumi KM et al.

Nucleic Acids Research, 2015

25712099 (PubMed )
Supplement: supp_gkv101_nar-01912-d-2014-File008.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."