Associated Papers
Blood-Based Genomic Alteration Signature for Predicting Progression-Free Survival in De Novo Metastatic Hormone-Sensitive Prostate Cancer: A Real-World Study.
Wang R et al.
Cancer Research Communications, 2025
41217768 (PubMed )
Supplement: crc-25-0384_supplementary_table_s2_suppst2.xlsx › Supplementary_Table_2
CDK12 regulates DNA repair genes by suppressing intronic polyadenylation.
Dubbury SJ et al.
Nature, 2018
CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion.
Tien JF et al.
Nucleic Acids Research, 2017
28334900 (PubMed )
Supplement: gkx187_Supp.zip › nar-01703-a-2016-File011.pdf
Ovarian Cancers Harboring Inactivating Mutations in CDK12 Display a Distinct Genomic Instability Pattern Characterized by Large Tandem Duplications.
Popova T et al.
Cancer Research, 2016
Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex.
Ekumi KM et al.
Nucleic Acids Research, 2015
Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity.
Bajrami I et al.
Cancer Research, 2014
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