Varaico: Literature-Extracted Genetic Variants

Gene:CDK12
Variant:p.D918G
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CDK12

NM_016507.4:p.D918G

Associated Papers

DNA2 protein destruction dictates DNA hyperexcision, cGAS-STING activation, and innate immune response in CDK12-deregulated cancers.

Sun R et al.

Proceedings of the National Academy of Sciences of the United States of America, 2025

Molecular consequences of acute versus chronic CDK12 loss in prostate carcinoma nominates distinct therapeutic strategies.

Frank S et al.

Biorxiv : the Preprint Server for Biology, 2025

39071291 (PubMed )
Supplement: media-1.xlsx › SU2C-I

Synthetic Lethal Targeting of CDK12-Deficient Prostate Cancer with PARP Inhibitors.

Chou J et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2024

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."