Varaico: Literature-Extracted Genetic Variants

Gene:CDK2
Variant:p.P45L
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CDK2

NM_001798.5:p.P45L

Associated Papers

Targeting G1-S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors.

Singh S et al.

Nature, 2025

40836083 (PubMed )
Supplement: 41586_2025_9433_MOESM4_ESM.zip › 2024-07-15654B-s4 › Table_S5_052925.xlsx › Tab_8-zscore_CDK2_C_T

Lysine acetylation regulates the interaction between proteins and membranes.

Okada AK et al.

Nature Communications, 2021

34753925 (PubMed )
Supplement: 41467_2021_26657_MOESM4_ESM.zip › Bioinformatics.zip › Datasets › Unused › PTMVAR_download.xlsx › Humsavar_overlap_2PSP_PTM5-14-1

Predicting the impact of single-nucleotide polymorphisms in CDK2-flavopiridol complex by molecular dynamics analysis.

Nagasundaram N et al.

Cell Biochemistry and Biophysics, 2013

A cancer-derived mutation in the PSTAIRE helix of cyclin-dependent kinase 2 alters the stability of cyclin binding.

Child ES et al.

Biochimica Et Biophysica Acta, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."