Associated Papers
Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a.
Burbidge O et al.
Structure (london, England : 1993), 2025
Targeted sequencing analysis of loci implicated in familial melanoma in a Greek cohort.
Kypreou K et al.
Journal of the European Academy of Dermatology and Venereology : Jeadv, 2024
CDKN2A Gene Mutations: Implications for Hereditary Cancer Syndromes.
Danishevich A et al.
Biomedicines, 2023
High- and intermediate-risk susceptibility variants in melanoma families from the Mediterranean area: A multicentre cohort from the MelaNostrum Consortium.
Pellegrini C et al.
Journal of the European Academy of Dermatology and Venereology : Jeadv, 2023
CDKN2A Polymorphism in Melanoma Patients in Colombian Population: A Case-Control Study.
Tovar-Parra JD et al.
Biomed Research International, 2020
Differential mechanisms of CDKN2A (p16) alteration in oral tongue squamous cell carcinomas and correlation with patient outcome.
Lim AM et al.
International Journal of Cancer, 2014
Familial melanoma-associated mutations in p16 uncouple its tumor-suppressor functions.
Jenkins NC et al.
The Journal of Investigative Dermatology, 2013
Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents.
Goldstein AM et al.
Journal of Medical Genetics, 2007
High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL.
Goldstein AM et al.
Cancer Research, 2006
Genetic susceptibility in familial melanoma from northeastern Italy.
Landi MT et al.
Journal of Medical Genetics, 2004
Functional impairment of melanoma-associated p16(INK4a) mutants in melanoma cells despite retention of cyclin-dependent kinase 4 binding.
Becker TM et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2001
Mutation testing in melanoma families: INK4A, CDK4 and INK4D.
Newton Bishop JA et al.
British Journal of Cancer, 1999
CDKN2A variants in a population-based sample of Queensland families with melanoma.
Aitken J et al.
Journal of the National Cancer Institute, 1999
Stability and folding of the tumour suppressor protein p16.
Tang KS et al.
Journal of Molecular Biology, 1999
Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group.
Soufir N et al.
Human Molecular Genetics, 1998
Germline mutations of the CDKN2 gene in UK melanoma families.
Harland M et al.
Human Molecular Genetics, 1997
The CDKN2A (p16) gene and human cancer.
Foulkes WD et al.
Molecular Medicine (cambridge, Mass.), 1997