Varaico: Literature-Extracted Genetic Variants

Gene:CDK6
Variant:p.Q12H
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CDK6

NM_001145306.2:p.Q12H

Associated Papers

Abemaciclib Does Not Have a Clinically Meaningful Effect on Pharmacokinetics of CYP1A2, CYP2C9, CYP2D6, and CYP3A4 Substrates in Patients with Cancer.

Turner PK et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2020

Phase 1 study of abemaciclib, an inhibitor of CDK 4 and 6, as a single agent for Japanese patients with advanced cancer.

Fujiwara Y et al.

Cancer Chemotherapy and Pharmacology, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."