Varaico: Literature-Extracted Genetic Variants

Gene:CDK9
Variant:p.D167N
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CDK9

NM_001261.4:p.D167N

Associated Papers

CDK9 interacts with a RanGTP-Importin-β complex to regulate erythroid enucleation.

Newton LM et al.

Journal of Cell Science, 2026

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S5

NUFIP1 integrates amino acid sensing and DNA damage response to maintain the intestinal homeostasis.

Ming H et al.

Nature Metabolism, 2025

39753713 (PubMed )
Supplement: 42255_2024_1179_MOESM25_ESM.pdf

Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation.

Mbonye U et al.

The Journal of Biological Chemistry, 2018

Structural and Functional Analysis of the Cdk13/Cyclin K Complex.

Greifenberg AK et al.

Cell Reports, 2016

Ser-634 and Ser-636 of Kaposi's Sarcoma-Associated Herpesvirus RTA are Involved in Transactivation and are Potential Cdk9 Phosphorylation Sites.

Tsai WH et al.

Frontiers in Microbiology, 2012

CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation.

Gordon V et al.

Molecular Endocrinology (baltimore, Md.), 2010

Cyclin-dependent kinase 9-cyclin K functions in the replication stress response.

Yu DS et al.

Embo Reports, 2010

Cyclin-dependent kinase-9 is a component of the p300/GATA4 complex required for phenylephrine-induced hypertrophy in cardiomyocytes.

Sunagawa Y et al.

The Journal of Biological Chemistry, 2010

Identification of HUGT1 as a potential BiP activator and a cellular target for improvement of recombinant protein production using a cDNA screening system.

Ku SC et al.

Molecules and Cells, 2009

The functional role of an interleukin 6-inducible CDK9.STAT3 complex in human gamma-fibrinogen gene expression.

Hou T et al.

The Journal of Biological Chemistry, 2007

The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling.

Bitoun E et al.

Human Molecular Genetics, 2007

P-TEFb is not an essential elongation factor for the intronless human U2 snRNA and histone H2b genes.

Medlin J et al.

The Embo Journal, 2005

The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein.

Garber ME et al.

Genes & Development, 1998

MCEF, the newest member of the AF4 family of transcription factors involved in leukemia, is a positive transcription elongation factor-b-associated protein.

Estable MC et al.

Journal of Biomedical Science, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."