Varaico: Literature-Extracted Genetic Variants

Gene:CDKN1A
Variant:p.P4P
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CDKN1A

NM_000389.5:p.P4P

Associated Papers

Oral Melanocytic Neoplasms: A Narrative Review.

Maldonado-Mendoza J

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2025

Excited-state observation of active K-Ras reveals differential structural dynamics of wild-type versus oncogenic G12D and G12C mutants.

Hansen AL et al.

Nature Structural & Molecular Biology, 2023

Single-center study on clinicopathological and typical molecular pathologic features of metastatic brain tumor.

Kim SH et al.

Journal of Pathology and Translational Medicine, 2023

Loss of HES1 Expression is Associated with Extracellular Matrix Remodeling and Tumor Immune Suppression in KRAS Mutant Colon Adenocarcinomas.

Wang L et al.

Research Square, 2023

Peptides That Block RAS-p21 Protein-Induced Cell Transformation.

Pincus MR et al.

Biomedicines, 2023

Potential genetic biomarker of Saudi Arabian patients with colorectal cancer.

Younis NS et al.

European Review for Medical and Pharmacological Sciences, 2022

Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics.

Tripathi S et al.

Computational and Structural Biotechnology Journal, 2022

34976316 (PubMed )
Supplement: mmc1.docx

Long-read sequencing for non-small-cell lung cancer genomes.

Sakamoto Y et al.

Genome Research, 2020

32887687 (PubMed )
Supplement: supp_gr.261941.120_Supplemental_material.docx

Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups.

Egan C et al.

Haematologica, 2020

Comprehensive Analysis of PTEN in Primary Cutaneous Melanoma.

Němejcová K et al.

Folia Biologica, 2020

A comprehensive evaluation of pathogenic mutations in primary cutaneous melanomas, including the identification of novel loss-of-function variants.

Ticha I et al.

Scientific Reports, 2019

Binimetinib, a novel MEK1/2 inhibitor, exerts anti-leukemic effects under inactive status of PI3Kinase/Akt pathway.

Sakakibara K et al.

International Journal of Hematology, 2019

A KRAS wild type mutational status confers a survival advantage in pancreatic ductal adenocarcinoma.

Windon AL et al.

Journal of Gastrointestinal Oncology, 2018

Comprehensive genomic profiling of 295 cases of clinically advanced urothelial carcinoma of the urinary bladder reveals a high frequency of clinically relevant genomic alterations.

Ross JS et al.

Cancer, 2016

Clonal status of actionable driver events and the timing of mutational processes in cancer evolution.

McGranahan N et al.

Science Translational Medicine, 2015

Peripheral lung adenocarcinomas with KRAS mutations are more likely to invade visceral pleura.

Raparia K et al.

Archives of Pathology & Laboratory Medicine, 2015

[K-RAS gene mutations in patients with non-small cell lung cancer].

Zhang Y et al.

Zhongguo Fei Ai Za Zhi = Chinese Journal of Lung Cancer, 2010

Rapid detection of K-ras mutations in bile by peptide nucleic acid-mediated PCR clamping and melting curve analysis: comparison with restriction fragment length polymorphism analysis.

Chen CY et al.

Clinical Chemistry, 2004

Augmentation of immune response by an analog of the antigenic peptide in a human T-cell clone recognizing mutated Ras-derived peptides.

Yokomizo H et al.

Human Immunology, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."