Varaico: Literature-Extracted Genetic Variants

Gene:CDKN1A
Variant:p.P24S
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CDKN1A

NM_000389.5:p.P24S

Associated Papers

Polymorphism at codon 31 of CDKN1A (p21) as a predictive factor for bevacizumab therapy in glioblastoma multiforme.

Cheng WY et al.

Bmc Cancer, 2023

TP53 and p21 (CDKN1A) polymorphisms and the risk of systemic lupus erythematosus.

Macedo JMB et al.

Advances in Rheumatology (london, England), 2023

Gene polymorphisms of cyclin-dependent kinase inhibitor and matrix metalloproteinase-9 in Sudanese patients with esophageal squamous cell carcinoma.

Eltayeb MM et al.

Molecular Genetics & Genomic Medicine, 2022

CDKN1A (p21 gene) polymorphisms correlates with age in esophageal cancer.

Kaya Z et al.

Molecular Biology Reports, 2022

Single nucleotide polymorphisms and the risk of developing a second primary cancer among head and neck cancer patients: a systematic literature review and meta-analysis.

Hoxhaj I et al.

Bmc Cancer, 2021

Analysis of polymorphisms, promoter methylation, and mRNA expression profile of maternal and placental P53 and P21 genes in preeclamptic and normotensive pregnant women.

Harati-Sadegh M et al.

Journal of Biomedical Science, 2019

Long telomeres cooperate with p53, MDM2, and p21 polymorphisms to raise pediatric solid tumor risk.

Borbora D et al.

Pediatrics International : Official Journal of the Japan Pediatric Society, 2019

Susceptibility of Multiple Primary Cancers in Patients With Head and Neck Cancer: Nature or Nurture?

Zhang WL et al.

Frontiers in Oncology, 2019

The effects of p21 gene C98A polymorphism on development of uterine leiomyoma in southeast Iranian women.

Salimi S et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2016

Roles of CDKN1A gene polymorphisms (rs1801270 and rs1059234) in the development of cervical neoplasia.

Vargas-Torres SL et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2016

Association of p53 and p21 polymorphisms with prostate cancer.

Sivoňová MK et al.

Biomedical Reports, 2015

Association of p21 3' UTR gene polymorphism with cancer risk: Evidence from a meta-analysis.

Li J et al.

Scientific Reports, 2015

The effects of two polymorphisms on p21cip1 function and their association with Alzheimer's disease in a population of European descent.

Yates SC et al.

Plos One, 2015

Quantitative Assessment the Relationship between p21 rs1059234 Polymorphism and Cancer Risk.

Huang YS et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2015

Cell cycle deregulation and TP53 and RAS mutations are major events in poorly differentiated and undifferentiated thyroid carcinomas.

Pita JM et al.

The Journal of Clinical Endocrinology and Metabolism, 2014

Genetic variants of p21 and p27 and hepatocellular cancer risk in a Chinese Han population: a case-control study.

Liu F et al.

International Journal of Cancer, 2013

The role of p21 3'UTR gene polymorphism in the risk of prostate cancer: a pilot study.

Sivoňová MK et al.

Molecular Medicine Reports, 2013

Genetic variants of p27 and p21 as predictors for risk of second primary malignancy in patients with index squamous cell carcinoma of head and neck.

Wang Z et al.

Molecular Cancer, 2012

[Susceptibility of chromosomal damage among workers exposed to vinyl chloride monomer].

Ji F et al.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi = Zhonghua Laodong Weisheng Zhiyebing Zazhi = Chinese Journal of Industrial Hygiene and Occupational Diseases, 2011

P21 Ser31Arg polymorphism and cervical cancer risk: a meta-analysis.

Li Y et al.

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society, 2011

P21(waf1/cip1) gene polymorphisms and possible interaction with cigarette smoking in esophageal squamous cell carcinoma in northeastern Iran: a preliminary study.

Taghavi N et al.

Archives of Iranian Medicine, 2010

Genetic polymorphisms of p21 and risk of second primary malignancy in patients with index squamous cell carcinoma of the head and neck.

Lei D et al.

Carcinogenesis, 2010

Risk of malignant pleural mesothelioma and polymorphisms in genes involved in the genome stability and xenobiotics metabolism.

Gemignani F et al.

Mutation Research, 2009

Mutational analysis of TP53, PTEN, PIK3CA and CTNNB1/beta-catenin genes in human herpesvirus 8-associated primary effusion lymphoma.

Boulanger E et al.

Haematologica, 2009

Association of genetic polymorphisms, mRNA expression of p53 and p21 with chronic benzene poisoning in a chinese occupational population.

Sun P et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2009

Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project.

Canova C et al.

Cancer Research, 2009

Genotype and haplotype analysis of cell cycle genes in sporadic colorectal cancer in the Czech Republic.

Polakova V et al.

Human Mutation, 2009

Influence of cancer-related gene polymorphisms on clinicopathological features in colorectal cancer.

Yoshiya G et al.

Journal of Gastroenterology and Hepatology, 2008

P21/ WAF1 and cyclin D1 variants and oral squamous cell carcinoma.

Gomes CC et al.

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2008

[Genetic polymorphism in cell cycle control genes and susceptibility of chromosomal damage in vinyl chloride monomer exposed workers.].

Qiu YL et al.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi = Zhonghua Laodong Weisheng Zhiyebing Zazhi = Chinese Journal of Industrial Hygiene and Occupational Diseases, 2007

Genetic polymorphisms of p21 are associated with risk of squamous cell carcinoma of the head and neck.

Li G et al.

Carcinogenesis, 2005

p21WAF1/CIP1 regulates the p300 sumoylation motif CRD1 through a C-terminal domain independently of cyclin/CDK binding.

Garcia-Wilson E et al.

Cell Cycle (georgetown, Tex.), 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."