Varaico: Literature-Extracted Genetic Variants

Gene:CDKN1A
Variant:p.S31R
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CDKN1A

NM_000389.5:p.S31R

Associated Papers

Role of human papillomavirus (HPV) variants and host genetic susceptibility in cervical carcinogenesis.

Singh A et al.

Archives of Microbiology, 2026

A scalable approach to resolving variants of uncertain significance.

Tejura M et al.

Biorxiv : the Preprint Server for Biology, 2026

41727046 (PubMed )
Supplement: media-7.xlsx › VarChAMP_data_supp_mat_PP

Association of Tumor Suppressor TP53 and TP21 Gene Polymoprhisms with Radiotherapy Induced Adverse Reactions in Head and Neck Cancer Patients.

Gudur AK et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2025

Low dose DNA methyltransferase inhibitors potentiate PARP inhibitors in homologous recombination repair deficient tumors.

Pacaud R et al.

Breast Cancer Research : Bcr, 2025

39819384 (PubMed )
Supplement: 13058_2024_1954_MOESM5_ESM.xlsx › Sheet1

Genomic and transcriptomic profiles associated with response to eribulin and nivolumab combination in HER-2-negative metastatic breast cancer.

Park C et al.

Cancer Immunology, Immunotherapy : Cii, 2024

39105849 (PubMed )
Supplement: 262_2024_3782_MOESM1_ESM.pdf

Genetic mutation patterns among glioblastoma patients in the Taiwanese population - insights from a single institution retrospective study.

Huang YF et al.

Cancer Gene Therapy, 2024

Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort.

Vanni I et al.

Journal of Translational Medicine, 2024

38750555 (PubMed )
Supplement: 12967_2024_5227_MOESM15_ESM.xlsx › S15

Molecular Basis and Natural History of Medullary Thyroid Cancer: It is (Almost) All in the RET.

Sahakian N et al.

Cancers, 2023

Polymorphism at codon 31 of CDKN1A (p21) as a predictive factor for bevacizumab therapy in glioblastoma multiforme.

Cheng WY et al.

Bmc Cancer, 2023

Indicators of HSV1 Infection, ECM-Receptor Interaction, and Chromatin Modulation in a Nuclear Family with Schizophrenia.

Huang YC et al.

Journal of Personalized Medicine, 2023

37763159 (PubMed )
Supplement: jpm-13-01392-s001.zip › Supplementary_Table_S3.xlsx › Variants

TP53 and p21 (CDKN1A) polymorphisms and the risk of systemic lupus erythematosus.

Macedo JMB et al.

Advances in Rheumatology (london, England), 2023

Association between CDKN1A gene rs1801270 polymorphisms and susceptibility to colorectal cancser in an Iranian population.

Zali N et al.

Nucleosides, Nucleotides & Nucleic Acids, 2023

Genomic characterization of lymphomas in patients with inborn errors of immunity.

Ye X et al.

Blood Advances, 2022

35687490 (PubMed )
Supplement: advancesADV2021006654-suppl4.xlsx › PL23

Responses to the Tepotinib in Gastric Cancers with MET Amplification or MET Exon 14 Skipping Mutations and High Expression of Both PD-L1 and CD44.

Sohn SH et al.

Cancers, 2022

35884507 (PubMed )
Supplement: cancers-14-03444-s001.zip › supplementary_material_Table_S1.xlsx › Kato_III

The Genomic Landscape of Corticotroph Tumors: From Silent Adenomas to ACTH-Secreting Carcinomas.

Andonegui-Elguera S et al.

International Journal of Molecular Sciences, 2022

Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses.

Kim SC et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2022

34918496 (PubMed )
Supplement: ADVS-9-2103360-s007.xlsx › Table_S3C

CDKN1A (p21 gene) polymorphisms correlates with age in esophageal cancer.

Kaya Z et al.

Molecular Biology Reports, 2022

Association between Molecular Genetic Markers of DNA Repair and Cell Cycle Control Genes and Response to Platinum-Based Chemotherapy in Ovarian Cancer Patients.

Zavarikina TM et al.

Bulletin of Experimental Biology and Medicine, 2021

Crosstalk of Cyclin-dependent kinase inhibitor 1A (CDKN1A) gene polymorphism with p53 and CCND1 polymorphism in breast cancer.

Akhter N et al.

European Review for Medical and Pharmacological Sciences, 2021

Interactions among variants in P53 apoptotic pathway genes are associated with neurologic deterioration and functional outcome after acute ischemic stroke.

Yi X et al.

Brain and Behavior, 2021

A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC).

Low JL et al.

Ebiomedicine, 2021

33529999 (PubMed )
Supplement: mmc2.xlsx › Table_S2

Association between tobacco substance usage and a missense mutation in the tumor suppressor gene P53 in the Saudi Arabian population.

Almutairi MH et al.

Plos One, 2021

Umbrella Review on Associations Between Single Nucleotide Polymorphisms and Lung Cancer Risk.

Li X et al.

Frontiers in Molecular Biosciences, 2021

34540891 (PubMed )
Supplement: DataSheet1.zip › Data_Sheet_---Supplementary_Additional_file › Supplementary_Additional_file › Supplementary_Additional_file_S2.docx

Identification of New Tumor-Related Gene Mutations in Chinese Gastrointestinal Stromal Tumors.

Feng Y et al.

Frontiers in Cell and Developmental Biology, 2021

34805171 (PubMed )
Supplement: Table6.XLS › 49_sample_result

The cell cycle regulatory gene polymorphisms TP53 (rs1042522) and MDM2 (rs2279744) in lung cancer: a meta-analysis.

Bulgakova O et al.

Vavilovskii Zhurnal Genetiki I Selektsii, 2020

Association of Molecular Genetic Markers of TP53, MDM2, and CDKN1A Genes with Progression-Free Survival of Patients with Ovarian Cancer after Platinum-Based Chemotherapy.

Zavarykina TM et al.

Bulletin of Experimental Biology and Medicine, 2020

A novel hotspot and rare somatic mutation p.A138V, at TP53 is associated with poor survival of pancreatic ductal and periampullary adenocarcinoma patients.

Saha G et al.

Molecular Medicine (cambridge, Mass.), 2020

32552660 (PubMed )
Supplement: 10020_2020_183_MOESM4_ESM.xlsx › Primers_For_Genotyping

Modulatory Role of Single Nucleotide Polymorphisms of Distinct Genetic Pathways on Clinical Behavior of Medullary Thyroid Carcinoma.

Mishra V et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2020

The effect of TP53 and P21 gene polymorphisms on papillary thyroid carcinoma susceptibility and clinical/pathological features.

Heidari Z et al.

Iubmb Life, 2020

Somatic mutations in the DNA repairome in prostate cancers in African Americans and Caucasians.

Yadav S et al.

Oncogene, 2020

32300177 (PubMed )
Supplement: 41388_2020_1280_MOESM3_ESM.xlsx › Main_Sheet_

Evaluation of TP53 Codon 72, P21 Codon 31, and MDM2 SNP309 Polymorphisms in Iranian Patients with Acute Lymphocytic Leukemia.

Lotfi Garavand A et al.

Reports of Biochemistry & Molecular Biology, 2020

P21 Ser31Arg and FGFR2 rs2981582 Polymorphisms as Risk Factors for Early Onset of Breast Cancer in Yogyakarta, Indonesia.

Purnomosari D et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2019

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

Fragoza R et al.

Nature Communications, 2019

31515488 (PubMed )
Supplement: 41467_2019_11959_MOESM9_ESM.xlsx › SD5_-_DUAL-FLUO

Association between MDM2 rs2279744, MDM2 rs937283, and p21 rs1801270 polymorphisms and retinoblastoma susceptibility.

Cao Q et al.

Medicine, 2018

Whole-Exome Sequencing Study of Extreme Phenotypes of NAFLD.

Kleinstein SE et al.

Hepatology Communications, 2018

Discovering novel SNPs that are correlated with patient outcome in a Singaporean cancer patient cohort treated with gemcitabine-based chemotherapy.

Limviphuvadh V et al.

Bmc Cancer, 2018

29751792 (PubMed )
Supplement: 12885_2018_4471_MOESM1_ESM.zip › TableS2R2.xlsx › Table_S2

Targeted exome sequencing of Korean triple-negative breast cancer reveals homozygous deletions associated with poor prognosis of adjuvant chemotherapy-treated patients.

Jeong HM et al.

Oncotarget, 2017

Preliminary evidence of polymorphisms of cell cycle regulatory genes and their roles in urinary tract urothelial cancer susceptibility and prognosis in a Taiwan population.

Lin YC et al.

Urologic Oncology, 2017

Whole exome analyses to examine the impact of rare variants on left ventricular traits in African American participants from the HyperGEN and GENOA studies.

Do AN et al.

Journal of Hypertension and Management, 2017

The effects of p21 gene C98A polymorphism on development of uterine leiomyoma in southeast Iranian women.

Salimi S et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2016

Roles of CDKN1A gene polymorphisms (rs1801270 and rs1059234) in the development of cervical neoplasia.

Vargas-Torres SL et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2016

Association between p21 Ser31Arg polymorphism and the development of cervical lesion in women infected with high risk HPV.

Lima G et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2016

Genetic variants in cell cycle control pathway confer susceptibility to aggressive prostate carcinoma.

Kibel AS et al.

The Prostate, 2016

Polymorphisms in DNA repair genes and breast cancer risk in Russian population: a case-control study.

Shadrina AS et al.

Clinical and Experimental Medicine, 2016

Somatic Variations in Cervical Cancers in Indian Patients.

Das P et al.

Plos One, 2016

27829003 (PubMed )
Supplement: pone.0165878.s001.xlsx › somatic_cosmic_hit.list

Association Between p21 Ser31Arg Polymorphism and Gastrointestinal Tract Tumor Risk: A Meta-analysis.

Dong Y et al.

Technology in Cancer Research & Treatment, 2015

Association of p53 rs1042522, MDM2 rs2279744, and p21 rs1801270 polymorphisms with retinoblastoma risk and invasion in a Chinese population.

Chen R et al.

Scientific Reports, 2015

Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine.

Simeon V et al.

International Journal of Molecular Sciences, 2015

Meta-analysis of angiotensin-converting enzyme insertion/deletion polymorphism and myocardial infarction in Han Chinese.

Zhao W et al.

Genetics and Molecular Research : Gmr, 2015

Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach.

Karageorgos I et al.

Human Genomics, 2015

26092435 (PubMed )
Supplement: 40246_2015_34_MOESM1_ESM.xlsx › FamilyB
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."