Varaico: Literature-Extracted Genetic Variants

Gene:CDKN1A
Variant:p.T57A
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CDKN1A

NM_000389.5:p.T57A

Associated Papers

JNKs function as CDK4-activating kinases by phosphorylating CDK4 and p21.

Colleoni B et al.

Oncogene, 2017

Mitotic p21Cip1/CDKN1A is regulated by cyclin-dependent kinase 1 phosphorylation.

Kreis NN et al.

Oncotarget, 2016

CDK1-dependent inhibition of the E3 ubiquitin ligase CRL4CDT2 ensures robust transition from S Phase to Mitosis.

Rizzardi LF et al.

The Journal of Biological Chemistry, 2015

CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point.

Bisteau X et al.

Plos Genetics, 2013

Cdk2-dependent Inhibition of p21 stability via a C-terminal cyclin-binding motif.

Zhu H et al.

The Journal of Biological Chemistry, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."