Varaico: Literature-Extracted Genetic Variants

Gene:CDKN1B
Variant:p.N66K
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CDKN1B

NM_004064.5:p.N66K

Associated Papers

Landscape of CDKN1B Mutations in Luminal Breast Cancer and Other Hormone-Driven Human Tumors.

Cusan M et al.

Frontiers in Endocrinology, 2018

Modification of p27 with O-linked N-acetylglucosamine regulates cell proliferation in hepatocellular carcinoma.

Qiu H et al.

Molecular Carcinogenesis, 2017

The unpredictable consequences of CDKN1B/p27Kip1 mutations in cancer.

Borriello A et al.

Cell Cycle (georgetown, Tex.), 2015

p27(Kip1) controls cytokinesis via the regulation of citron kinase activation.

Serres MP et al.

The Journal of Clinical Investigation, 2012

RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.

Larrea MD et al.

Proceedings of the National Academy of Sciences of the United States of America, 2009

Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels.

Morishita D et al.

Cancer Research, 2008

p27Kip1 localization depends on the tumor suppressor protein tuberin.

Rosner M et al.

Human Molecular Genetics, 2007

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization.

Fujita N et al.

The Journal of Biological Chemistry, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."