Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2A
Variant:p.E2fs
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CDKN2A

NM_000077.5:p.E2fs

Associated Papers

An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastoma.

Fraire CR et al.

Genes & Development, 2025

Retinoma: An overview.

Toumasis PN et al.

Pediatric Investigation, 2025

P16INK4a Regulates ROS-Related Autophagy and CDK4/6-Mediated Proliferation: A New Target of Myocardial Regeneration Therapy.

Sun J et al.

Oxidative Medicine and Cellular Longevity, 2023

Linc00441 interacts with DNMT1 to regulate RB1 gene methylation and expression in gastric cancer.

Zhou J et al.

Oncotarget, 2018

From General Aberrant Alternative Splicing in Cancers and Its Therapeutic Application to the Discovery of an Oncogenic DMTF1 Isoform.

Tian N et al.

International Journal of Molecular Sciences, 2017

Islet biology, the CDKN2A/B locus and type 2 diabetes risk.

Kong Y et al.

Diabetologia, 2016

Functional Studies on Primary Tubular Epithelial Cells Indicate a Tumor Suppressor Role of SETD2 in Clear Cell Renal Cell Carcinoma.

Li J et al.

Neoplasia (new York, N.y.), 2016

The Mdm network and its regulation of p53 activities: a rheostat of cancer risk.

Eischen CM et al.

Human Mutation, 2014

Stable form of JAB1 enhances proliferation and maintenance of hematopoietic progenitors.

Mori M et al.

The Journal of Biological Chemistry, 2008

Mitochondrial p32 is a critical mediator of ARF-induced apoptosis.

Itahana K et al.

Cancer Cell, 2008

E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex.

Rayman JB et al.

Genes & Development, 2002

Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo.

Ezhevsky SA et al.

Molecular and Cellular Biology, 2001

Cdk2-dependent phosphorylation and functional inactivation of the pRB-related p130 protein in pRB(-), p16INK4A(+) tumor cells.

Cheng L et al.

The Journal of Biological Chemistry, 2000

E2F and the molecular mechanisms of early cell-cycle control.

La Thangue NB

Biochemical Society Transactions, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."