Varaico: Literature-Extracted Genetic Variants

Gene:CDKN2B
Variant:p.G12C
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CDKN2B

NM_004936.4:p.G12C

Associated Papers

Baseline mutational profiles of patients with carcinoma of unknown primary origin enrolled in the CUPISCO study.

Westphalen CB et al.

Esmo Open, 2023

37922692 (PubMed )
Supplement: mmc1.docx

Dual blockade of BRD4 and ATR/WEE1 pathways exploits ARID1A loss in clear cell ovarian cancer.

Kinose Y et al.

Research Square, 2023

Loss of HES1 Expression is Associated with Extracellular Matrix Remodeling and Tumor Immune Suppression in KRAS Mutant Colon Adenocarcinomas.

Wang L et al.

Research Square, 2023

Effects of TP53 Mutations and miRs on Immune Responses in the Tumor Microenvironment Important in Pancreatic Cancer Progression.

McCubrey JA et al.

Cells, 2022

Genomic Features of Organ-Specific Metastases in Lung Adenocarcinoma.

Feng A et al.

Frontiers in Oncology, 2022

In vitro behavior and UV response of melanocytes derived from carriers of CDKN2A mutations and MC1R variants.

Hernando B et al.

Pigment Cell & Melanoma Research, 2019

The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition.

Goodwin J et al.

Nature Communications, 2017

28548087 (PubMed )
Supplement: ncomms15503-s1.pdf

Comprehensive genomic profiling of 295 cases of clinically advanced urothelial carcinoma of the urinary bladder reveals a high frequency of clinically relevant genomic alterations.

Ross JS et al.

Cancer, 2016

Germline hemizygous deletion of CDKN2A-CDKN2B locus in a patient presenting with Li-Fraumeni syndrome.

Chan SH et al.

Npj Genomic Medicine, 2016

29263814 (PubMed )
Supplement: npjgenmed201615-s1.doc

Population-based prevalence of CDKN2A mutations in Utah melanoma families.

Eliason MJ et al.

The Journal of Investigative Dermatology, 2006

Germline splicing mutations of CDKN2A predispose to melanoma.

Loo JC et al.

Oncogene, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."