Associated Papers
Regulation of Human Hydrolases and Its Implications in Pharmacokinetics and Pharmacodynamics.
Jung SM et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2024
Regulation of carboxylesterases and its impact on pharmacokinetics and pharmacodynamics: an up-to-date review.
Liu Y et al.
Expert Opinion on Drug Metabolism & Toxicology, 2024
Predicting the Effects of CYP2C19 and Carboxylesterases on Vicagrel, a Novel P2Y12 Antagonist, by Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Approach.
Liu S et al.
Frontiers in Pharmacology, 2020
Clinical implications of genetic variation in carboxylesterase drug metabolism.
Chen F et al.
Expert Opinion on Drug Metabolism & Toxicology, 2018
Interindividual variability of carboxymethylenebutenolidase homolog, a novel olmesartan medoxomil hydrolase, in the human liver and intestine.
Ishizuka T et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2013
Haplotypes and a novel defective allele of CES2 found in a Japanese population.
Kim SR et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2007
Functional characterization of three naturally occurring single nucleotide polymorphisms in the CES2 gene encoding carboxylesterase 2 (HCE-2).
Kubo T et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2005
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