Varaico: Literature-Extracted Genetic Variants

Gene:CFH
Variant:p.Y420H
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CFH

NM_000186.4:p.Y420H

Associated Papers

The Complement Factor H (Y402H) risk polymorphism for age-related macular degeneration affects metabolism and response to oxidative stress in the retinal pigment epithelium.

Shang P et al.

Free Radical Biology & Medicine, 2024

Association of the Complement Factor H Y402H Polymorphism and Response to Anti-Vascular Endothelial Growth Factor Treatment in Age-Related Macular Degeneration: An Updated Meta-Analysis.

Roshanshad A et al.

Ophthalmic Research, 2024

Oxidative stress in retinal pigment epithelium degeneration: from pathogenesis to therapeutic targets in dry age-related macular degeneration.

Maurya M et al.

Neural Regeneration Research, 2023

Associations between CYP2J2 (-76G>T) rs890293 polymorphism and age-related macular degeneration.

Liutkeviciene R et al.

Biomedical Papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2020

Association of the CFH Y402H Polymorphism with the 1-Year Response of Exudative AMD to Intravitreal Anti-VEGF Treatment in the Brazilian Population.

Medina FMC et al.

Ophthalmic Research, 2019

Evaluation of serum SLCO1B1 levels and genetic variants of SLCO1B1 rs4149056 and rs2306283 in patients with early and exudative age-related macular degeneration.

Liutkeviciene R et al.

Gene, 2018

Evaluation of CFH Y402H polymorphism and CFHR3/CFHR1 deletion in age-related macular degeneration patients from Brazil.

Dezidério Sacconi DP et al.

Ophthalmic Genetics, 2016

Defects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration.

Ferrington DA et al.

Progress in Retinal and Eye Research, 2016

Pharmacogenetics of Complement Factor H Y402H Polymorphism and Treatment of Neovascular AMD with Anti-VEGF Agents: A Meta-Analysis.

Chen G et al.

Scientific Reports, 2015

Association of complement factor H gene polymorphisms with age-related macular egeneration susceptibility.

Hao XF et al.

International Journal of Clinical and Experimental Pathology, 2015

CFH (rs1410996), HTRA1 (rs112000638) and ARMS2 (rs10490923) gene polymorphisms are associated with AMD risk in Spanish patients.

Cruz-González F et al.

Ophthalmic Genetics, 2014

Functional effect of Saffron supplementation and risk genotypes in early age-related macular degeneration: a preliminary report.

Marangoni D et al.

Journal of Translational Medicine, 2013

Complement factor h autoantibodies and age-related macular degeneration.

Dhillon B et al.

Investigative Ophthalmology & Visual Science, 2010

Gene-environment interactions in ocular diseases.

Sacca SC et al.

Mutation Research, 2009

The role of inflammation in the pathogenesis of age-related macular degeneration.

Donoso LA et al.

Survey of Ophthalmology, 0

Associations between Rs4244285 and Rs762551 gene polymorphisms and age-related macular degeneration.

Stasiukonyte N et al.

Ophthalmic Genetics, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."