Associated Papers
A scalable approach to resolving variants of uncertain significance.
Tejura M et al.
Biorxiv : the Preprint Server for Biology, 2026
41727046 (PubMed )
Supplement: media-7.xlsx › VarChAMP_data_supp_mat_PP
Structural studies offer a framework for understanding the role of properdin in the alternative pathway and beyond.
Pedersen DV et al.
Immunological Reviews, 2023
Systematic analysis of the intersection of disease mutations with protein modifications.
Simpson CM et al.
Bmc Medical Genomics, 2019
31345222 (PubMed )
Supplement: 12920_2019_543_MOESM6_ESM.xlsx › S5C
Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Pedersen DV et al.
Frontiers in Immunology, 2019
Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b.
van den Bos RM et al.
Frontiers in Immunology, 2019
Compound heterozygous mutations in IL10RA combined with a complement factor properdin mutation in infantile-onset inflammatory bowel disease.
Jung ES et al.
European Journal of Gastroenterology & Hepatology, 2018
Functional and structural insight into properdin control of complement alternative pathway amplification.
Pedersen DV et al.
The Embo Journal, 2017
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