Associated Papers
Correction: Role of Hydrophobic Amino-Acid Side-Chains in the Narrow Selectivity Filter of the CFTR Chloride Channel Pore in Conductance and Selectivity.
Linsdell P
The Journal of Membrane Biology, 2024
Role of Hydrophobic Amino-Acid Side-Chains in the Narrow Selectivity Filter of the CFTR Chloride Channel Pore in Conductance and Selectivity.
Linsdell P
The Journal of Membrane Biology, 2023
Strategies for cystic fibrosis transmembrane conductance regulator inhibition: from molecular mechanisms to treatment for secretory diarrhoeas.
de Jonge HR et al.
Febs Letters, 2020
Contribution of the eighth transmembrane segment to the function of the CFTR chloride channel pore.
Negoda A et al.
Cellular and Molecular Life Sciences : Cmls, 2019
Molecular structure of the ATP-bound, phosphorylated human CFTR.
Zhang Z et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018
Structural mechanisms of CFTR function and dysfunction.
Hwang TC et al.
The Journal of General Physiology, 2018
Contribution of a leucine residue in the first transmembrane segment to the selectivity filter region in the CFTR chloride channel.
Negoda A et al.
Biochimica Et Biophysica Acta. Biomembranes, 2017
Conformational changes opening and closing the CFTR chloride channel: insights from cysteine scanning mutagenesis.
El Hiani Y et al.
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 2014
Cysteine scanning of CFTR's first transmembrane segment reveals its plausible roles in gating and permeation.
Gao X et al.
Biophysical Journal, 2013
Locating a plausible binding site for an open-channel blocker, GlyH-101, in the pore of the cystic fibrosis transmembrane conductance regulator.
Norimatsu Y et al.
Molecular Pharmacology, 2012
Cystic fibrosis transmembrane conductance regulator: a molecular model defines the architecture of the anion conduction path and locates a "bottleneck" in the pore.
Norimatsu Y et al.
Biochemistry, 2012
Differential contribution of TM6 and TM12 to the pore of CFTR identified by three sulfonylurea-based blockers.
Cui G et al.
Pflugers Archiv : European Journal of Physiology, 2012
Cystic fibrosis transmembrane conductance regulator: temperature-dependent cysteine reactivity suggests different stable conformers of the conduction pathway.
Liu X et al.
Biochemistry, 2011
Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore.
Wang W et al.
The Journal of General Physiology, 2011
Changes in accessibility of cytoplasmic substances to the pore associated with activation of the cystic fibrosis transmembrane conductance regulator chloride channel.
El Hiani Y et al.
The Journal of Biological Chemistry, 2010
Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation.
Bai Y et al.
The Journal of General Physiology, 2010
Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore.
Alexander C et al.
Biochemistry, 2009
State-dependent access of anions to the cystic fibrosis transmembrane conductance regulator chloride channel pore.
Fatehi M et al.
The Journal of Biological Chemistry, 2008
Conformational changes in a pore-lining helix coupled to cystic fibrosis transmembrane conductance regulator channel gating.
Beck EJ et al.
The Journal of Biological Chemistry, 2008
Probing the structural and functional domains of the CFTR chloride channel.
Akabas MH et al.
Journal of Bioenergetics and Biomembranes, 1997
Identification of cystic fibrosis transmembrane conductance regulator channel-lining residues in and flanking the M6 membrane-spanning segment.
Cheung M et al.
Biophysical Journal, 1996